نتایج جستجو برای: cd55
تعداد نتایج: 1341 فیلتر نتایج به سال:
Traditional therapeutic communities (TCs) are characterized by confrontational group therapy, treatment phases, a tenure-based resident hierarchy, and long-term residential care. Many TCs have modified the structure and intensity of the traditional model, tailored services for specific client populations, and hired more professionally trained staff. This study examines the extent to which modif...
Sloand et al1 report that in human red blood cells (RBCs) the paroxysmal nocturnal hemoglobinuria (PNH) defect can be corrected by transfer of glycosylphosphatidylinositol (GPI)-anchored proteins to GPI-deficient cells. It has been demonstrated before by a number of authors that cell-to-cell transfer of GPI-anchored proteins can occur, and I have no doubt that a similar event also takes place b...
The human complement regulator CD55 is a key molecule protecting self-cells from complement-mediated lysis. X-ray diffraction and analytical ultracentrifugation data reveal a rod-like arrangement of four short consensus repeat (SCR) domains in both the crystal and solution. The stalk linking the four SCR domains to the glycosylphosphatidylinositol anchor is extended by the addition of 11 highly...
CD97 is a member of a new subgroup of seven-span transmembrane (7-TM) molecules which belong to the secretin receptor superfamily. Different from other members of the secretin receptor family, these recently characterized molecules have extended extracellular regions comprising several EGF domains near the NH2 terminus. We recently demonstrated that the extracellular part of CD97 is involved in...
from Plasmodium falciparum (Pf) is an important concern1. Direct destruction of RBCs following Pf infection cannot account for the degree of anaemia observed during malaria infection instead it has been suggested that the destruction of uninfected RBCs is a major cause of haemoglobin loss2. Recent evidence suggests that RBC complement regulatory proteins are involved in malaria associated anaem...
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