We enjoyed reading the article by Esteve-Taboada et al.,1 but were disappointed by their interpretation of their data. Their optical model has important limitations that make it inappropriate to make broad clinical generalizations from their findings. First, the “aberration-free” eye model is highly artificial. In particular, the absence of any spherical aberration is relevant to only a small p...

PURPOSE To investigate corneal spherical aberration and corneal asphericity after small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK). METHODS This study enrolled 70 patients having SMILE and 64 subjects receiving FS-LASIK. The preoperative spherical equivalent (SE) was -5.83 ± 1.23 diopters (D) and -6.20 ± 1.52 D, respectively. T...

The invention of spherical aberration correctors has been the most significant contribution to the field of transmission electron microscopy since the field emission gun. Chromatic and spherical aberration, well known from optics, also play a role in electron microscopy. Lens aberrations are not unique to the magnetic lenses used in electron microscopes, but rather a fundamental problem of opti...

The technological developments in the design of an adaptive optical scanning acoustic microscope are described. Its two key elements include a multi-channel acoustic wavefront detector to detect the acoustic wavefront aberration and a highly adaptive acoustic source to correct for the effects of aberration. We present experimental images acquired with the instrument that indicate the degree of ...

We show a link between two apparently unrelated areas, namely uniformity and minimum aberration, both of which have been of substantial recent interest. Speciically, with reference to regular fractions of two-level factorials, we derive an expression for the centered L 2-discrepancy measure for uniformity in terms of the wordlength pattern. This result indicates, in particular, an excellent beh...

A contralateral bundle branch block (BBB) aberration during tachycardia with a preexisting BBB strongly suggests the presence of ventricular tachycardia. We report on a middle-aged, female patient presented with wide QRS tachycardia. The patient had orthodromic atrioventricular tachycardia with a left BBB aberration in the presence of a preexisting right BBB due to an abnormal His-Purkinje syst...

The classical cytogenetic assay relies on the scoring of chromosomal damage in cells at metaphase. According to the standard protocol the analysis is confined to cells at the 1st post-irradiation mitosis collected at one, early sampling time. For sparsely ionizing radiation this protocol allows a reasonable estimate of chromosomal damage, because in all commonly used cell system no or only a sl...

The dilated, round pupils of a species of suckermouth armoured catfish (Liposarcus pardalis) constrict slowly on illumination (over 35-40 min) to form crescent-shaped apertures. Ray tracing of He-Ne laser beams shows that the lenses of a related species (Pterygoplichthys etentaculus), which also has a crescent-shaped pupil, are well corrected for longitudinal spherical aberration, suggesting th...

Anthracycline antibiotics are widely used in cancer chemotherapy. Doxorubicin and Idarubicin, topoisomerase-targeting anthracyclines, were examined for their effect on chromosomal aberration and micronucleus induction in cultured human lymphocytes employing lymphocyte transformation test and cytokinesis-blocked micronucleus (CBMN) assay. A statistically significant dose-dependent increase in mi...