Hydrophobicity of a protein is considered to be one of the major intrinsic factors dictating the protein aggregation propensity. Understanding how protein hydrophobicity is determined is, therefore, of central importance in preventing protein aggregation diseases and in the biotechnological production of human therapeutics. Traditionally, protein hydrophobicity is estimated based on hydrophobic...

Alicyclobacillus sp. are acidothermophilic bacteria frequently contaminating fruit based products (juices and juice concentrates). These sporulating bacteria are able to survive at elevated temperatures and highly acidic environments which causes difficulties in their removal from industrial environments. Although numerous literature data examine Alicyclobacillus sp. presence in fruit based pro...

The aim of this study was to promote resistance in Salmonella enterica serovar Enteritidis, Typhimurium, and Virchow to commonly used antibacterials and to identify mechanisms underlying any resistance obtained. Strains were exposed to various biocides and following each passage adaptive resistance was recorded. Permeability changes in the outer membrane, including LPS, cell surface charge and ...

In the present study we have utilized the structural framework of the analog GS14K4 (cyclo(VKLd-KVd-YPL KVKLd-YP, where d denotes a d-amino acid)), to examine the role of hydrophobicity in microbial activity and specificity. The hydrophobicity of GS14K4 was systematically altered by residue replacements in the hydrophobic sites of the molecule to produce a series of analogs that were either les...

the current research was planned to investigate the effect of maleic anhydride (man) and glycidyl methacrylate (gma) treatments on morphological and physical properties of the hornbeam wood-styrene composite. test samples were divided according to astm d4446-05 to control and treated with man, st, man/st and man /st/gma. treatment was performed by vacuum- pressure method using a experimental cy...