Cooperative interactions among the binding of multiple signaling molecules is a common mechanism for enhancing the sensitivity of biological signaling systems. It is widely assumed that this increase in sensitivity of the mean response implies the ability to detect smaller signals. We show that, quite generally, there is a component of the noise in such systems that can be traced to the random ...

ABSTRACT- Lactic acid bacteria are commonly found in the gastrointestinal tract of various endothermic animals and humans, in milk, dairy and seafood products and on some plant surfaces. The aim of this study was to investigate the inhibitory effect of isolated lactic acid bacteria from intestines of narrow-barred Spanish mackerel (Scomberomorus commerson) on Listeria innocua growth. Five strai...

background: endometriosis is a complex estrogen-dependent disease that is defined as the presence of endometrial gland and stroma outside the uterine cavity. although the exact mechanism for the development of endometriosis remains unclear, there is a large body of research data and circumstantial evidence that suggests a crucial role of estrogen in the establishment and maintenance of this dis...

aquatic environments are often contaminated by various industrial, agricultural and domestic sewage, while different pesticides have markedly different effects on aquatic life. scenedesmus spp. are often used as an indicator to show changes in physico-chemical and environmental conditions of the aquatic ecosystems. this study aimed to investigate the effects of different concentrations of pesti...

Background: Promoter hyper-methylation of tumor suppressor genes is a common event that occurs in cancer. As methylation is a reversible modification, agents capable of reversing an abnormal methylation status should help to combat cancer. 5-Aza-CdR is a DNA methyl-transferase inhibitor. The present study aimed to evaluate the effect of 5-Aza-CdR on the proliferation of human pancreatic cancer ...

There is a recent trend of using lactic acid bacteria for the production gamma-aminobutyric (GABA). This study described method that combines fermentation and self-buffered whole-cell catalysis efficient GABA Levilactobacillus brevis CD0817. Upon completion fermentation, cells were recovered to conduct by which substrate L-glutamic was catalytically decarboxylated GABA. itself maintained acidit...

The 2-(methylamino) pyridine, L, reacts with CuCl in THF to give hexameric copper (I) complex, [CuCl(L)]6. The molecular structure has been determined by using single-crystal X-ray diffraction method. The complex crustallizes in the monoclinic space group P21/n with four molecules per unit cell. The unit cell dimensions are a = 8.3495 (15), b = 15.622 (6), and c = 17.0...

In this study, the antibacterial and cytotoxic activities of some amino acid methyl esters (L-methionine, L-phenylalanine, L-histidine, L-lysine, L-tryptophan, L-tyrosine) were investigated. The effect ester compounds on performance was determinated against Gram-negative Gram-positive bacteria. cell viability investigated cancerous non-cancerous lines using MTS assay. results showed substances ...

Introduction: Introduction: Molecular components within the microenvironment act upon cell growth, survival/apoptosis, and proliferation. Immune system cells respond to molecules produced by the tumor and released in the surrounding microenvironment, such as cytokines, chemokines, and growth factors. This study aimed to identify the effects of tumor environment on monocyte-macrophage cell linea...