Radiation-induced damage to the bone is characterised by four main pathological findings: osteoporosis, bone-marrow fibrosis, trabecular microfractures and disseminated areas of focal necrosis. The complications of radiotherapy affecting hip and pelvis are well known, but septic arthritis of the hip joint following pelvic irradiation is a rare occurrence. Radiation-induced damage associated wit...

BACKGROUND Outcome data on two-stage revision surgery for deep infection after septic hip arthritis are limited and inconsistent. This study presents the medium-term results of a new, standardized two-stage arthroplasty with preformed hip spacers and cementless implants in a consecutive series of adult patients with septic arthritis of the hip treated according to a same protocol. METHODS Nin...

The formation of polyacids in a glass-ionomer cement was computationally modeled. polyacid modelled is an oligomer made up three molecules: acrylic acid, itaconic acid and additional molecule that acts as spacer group between the previous two. Acryloyl meta-acryloyl derivatives some amino acids related molecules such N-vinyl pyrrolidone caprolactam were used groups. Some these have been previou...

BACKGROUND Antibiotic-impregnated bone cement spacer (ACS) with tobramycin ± vancomycin is commonly used in a 2-stage replacement of infected prosthetic joints. This procedure has been associated with development of acute kidney injury (AKI). OBJECTIVE To determine the incidence and risk factors for AKI after implantation of tobramycin-impregnated ACS. METHODS This prospective, observationa...

We present a series of 48 patients with infected total knee replacements managed by the use of articulating cement spacers and short-term parenteral antibiotic therapy in the postoperative period. All patients had microbiological and/or histological confirmation of infection at the first stage of their revision. They all underwent re-implantation and had a mean follow-up of 48.5 months (26 to 8...

Wei-Hsiu Hsu, MD 14 Division of Sports Medicine 15 Department of Orthopedic Surgery 16 Chang Gung Memorial Hospital at Chia Yi 17 Address: No 6, West section, Chia Pu Road 18 Puzih, Chia Yi Hsien 613 19 Taiwan 20 Tel 886-5-3621000 ext 2855 21 E mail: [email protected] 22 23 Kuo-Ti Peng: [email protected] 24 Liang-Tseng Kuo: [email protected] 25 Wei-Hsiu Hsu: [email protected] 26 Tsan-Wen Huang...

Fungal prosthetic joint infections (PJI) and reports of their clinical investigation are rare. In addition, there has been little evidence regarding the outcome of the two-stage exchange protocol for the treatment of fungal PJI. In order to investigate the risk factors and clinical, microbiological and pathological features of fungal PJIs, as well as the effects of the two-stage exchange protoc...

Spacers are used in spiral wound and plate and frame membrane modules to create flow channels between adjacent membrane layers and mix fluid within the flow channel. Flow through the spacer has a significant beneficial impact on mixing and resulting mass transfer rates but is accompanied by an undesirable increase in pressure drop. Computational Fluid Dynamics (CFD) is a common tool used to eva...