نتایج جستجو برای: cerebral salt wasting

تعداد نتایج: 268974  

2015
Yeon Jin Jeon Hyun Young Lee In Ah Jung Won-Kyoung Cho Bin Cho Byung-Kyu Suh

Cerebral salt-wasting syndrome (CSWS) is a rare disease characterized by a extracellular volume depletion and hyponatremia induced by marked natriuresis. It is mainly reported in patients who experience a central nervous system insult, such as cerebral hemorrhage or encephalitis. The syndrome of inappropriate antidiuretic hormone secretion is a main cause of severe hyponatremia after hematopoie...

Journal: :Arquivos de neuro-psiquiatria 2007
Ana P D Cardoso Desanka Dragosavac Sebastião Araújo Antonio L E Falcão Renato G G Terzi Margaret de Castro Fabiana G Marcondes Taís G Melo Rosmari A R A Oliveira Eliana A Cintra

BACKGROUND Cerebral salt wasting syndrome (CSWS), syndrome of inappropriate antidiuretic hormone secretion (SIADH) and diabetes insipidus (DI) are frequently found in postoperative neurosurgery. PURPOSE To identify these syndromes following neurosurgery. METHOD The study included 30 patients who had been submitted to tumor resection and cerebral aneurysm clipping. Sodium levels in serum and...

Journal: :Critical care medicine 2006
Neeraj S Naval Robert D Stevens Marek A Mirski Anish Bhardwaj

BACKGROUND The care of patients with aneurysmal subarachnoid hemorrhage has evolved significantly with the advent of new diagnostic and therapeutic modalities. Although it is believed that these advances have contributed to improved outcomes, considerable uncertainty persists regarding key areas of management. OBJECTIVE To review selected controversies in the management of aneurysmal subarach...

Journal: :Endocrine regulations 2000
L Pinterova M Garami Z Pribilincova R Behulova R Mezenska M Lukacova S Zorad

OBJECTIVE To analyse 21-hydroxylase gene for 8 most common mutations in patients with salt-wasting type of congenital adrenal hyperplasia. METHODS Allele specific PCR performed on 8 salt-wasting CAH patients and their 23 healthy relatives. RESULTS Two patients were homozygous for 8 bp deletion in exon 3, while 6 patients were homozygous for intron 2 splice mutation. Mutant allele for splice...

Journal: :Hormone research in paediatrics 2016
Carla Bizzarri Stefania Pedicelli Marco Cappa Stefano Cianfarani

In newborns and infants, dehydration and salt wasting represent a relatively common cause of admission to hospital and may result in life-threatening complications. Kidneys are responsible for electrolyte homoeostasis, but neonatal kidneys show low glomerular filtration rate and immaturity of the distal nephron, leading to reduced ability to concentrate urine. High extrarenal fluid losses often...

Journal: :Journal of the American Society of Nephrology : JASN 2016
Andrew S Terker Bethzaida Yarbrough Mohammed Z Ferdaus Rebecca A Lazelle Kayla J Erspamer Nicholas P Meermeier Hae J Park James A McCormick Chao-Ling Yang David H Ellison

Excess aldosterone is an important contributor to hypertension and cardiovascular disease. Conversely, low circulating aldosterone causes salt wasting and hypotension. Aldosterone activates mineralocorticoid receptors (MRs) to increase epithelial sodium channel (ENaC) activity. However, aldosterone may also stimulate the thiazide-sensitive Na(+)-Cl(-) cotransporter (NCC). Here, we generated mic...

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