AIM To evaluate ventriculo-cisternal perfusion as a method for measuring cerebrospinal fluid formation rate, calculated by means of the Heisey et al equation. Method. All experiments were carried out on anesthetized domestic cats fixed in the sphinx position in a stereotaxic frame. Ventriculo-cisternal perfusion was used at an intracranial pressure of -10 cm H2O at different perfusion rates (32...

There are few data in the literature on the distribution of sodium between serum and cerebrospinal fluid. Mestrezat (1) determined the concentration of individual inorganic elements on a mixture of cerebrospinal fluid from twenty normal individuals and obtained a value of 322 mg. per 100 cc. for sodium. Pincus and Kramer (2) and Weston and Howard (3) have published short series of determination...

The 51st Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida was held in the University of Heidelberg, Department of Neurosurgery at the invitation of Professor Andreas Unterberg and Dr. Alfred Aschoff. We are indebted to Alfred for his hard work in making the meeting such a success. Scientific sessions were held in the impressive auditorium of the new Kopfklinic and ...

Since the invention of the first implantable shunt valve by Nulsen and Spitz (12) almost 50 years ago, there has been a remarkable number of ingenious modifications and new designs of shunt equipment to treat pediatric hydrocephalus. These developments were in response to the immediately evident high shunt failure rate. These designs included antisiphon devices (15), on-off devices, gravity-act...

Alzheimer's disease is known to be the most common form of dementia in the elderly. It is clinically characterized by impairment of cognitive functions, as well as changes in personality, behavioral disturbances and an impaired ability to perform activities of daily living. To date, there are no effective ways to cure or reverse the disease. Genetic studies of early-onset familial Alzheimer's d...

Objective To discuss the roles of magnetic resonance imaging (MRI) and cerebrospinal fluid analysis in the identification of central nervous system associated infection and provide a reference for the diagnosis and treatment of central nervous system associated infectious diseases. Methods Seventy-six patients who developed central nervous system infection and were admitted into the Henan Peo...

Passot (1913) suggested that there was a greater chance of growing an organism from the cerebrospinal fluid if a technique were employed similar to that used in blood culture and a large volume of cerebrospinal fluid added to fluid media rather than a single loop of deposit. Most hospitals and textbooks, however, seem to favour culture of the deposit only. In this laboratory the results obtaine...

Investigation of 67 patients with neurological disorders (excluding meningitis) showed a mean level of Mg in cerebrospinal fluid of 1.93 +/- 0.03 mEq./l. These figures are significantly lower than earlier figures published in the literature. Patients with polyradiculo-neuritis do not show the fall in cerebrospinal fluid Mg levels reported in cases of infective meningitis. The level of Mg in cer...

INTRODUCTION Spontaneous cerebrospinal fluid leakage is usually caused by developmental abnormalities and is rare, accounting for approximately 5% of the cases of cerebrospinal fluid (CSF) leakage. To the best of our knowledge, clival dysplasia-caused CSF rhinorrhea has never been reported in the neurosurgical field. CONCLUSION Spontaneous cerebrospinal fluid rhinorrhea is often treated by su...

The activity of blood clotting factors has been investigated in cerebrospinal fluid. No cephalin-like activity was found in cerebrospinal fluid but prothrombin activity averaged about 0.5% of normal plasma activity. The activity of factor VII was negligible in almost all cases. The activity of antihaemophilic factors showed great variation but in the majority of cases it did not exceed 1% of no...