Cervical cancer is a preventable disease. The risk factors for the development of cervical cancer include both biologic factors and social factors. In the United States, the leading risk factor for the development of cervical cancer is not having a Pap smear for five years prior to the diagnosis of cancer. In low and middle income countries, cervical cancer incidence and mortality are directly ...

AIMS To investigate metastasis associated in colon cancer 1 (MACC1) expression in cervical cancer. METHODS One hundred and four paraffin-embedded cervical cancer specimens were immunohistochemically analyzed for MACC1 expression. The expression of MACC1 in 8 pairs of cervical cancer and adjacent normal cervical tissues were detected by Real-time PCR. RESULTS MACC1 expression was upregulated...

OBJECTIVE This study aimed to evaluate the relationship between forkhead box P3 (Foxp3) expression and clinicopathological characteristics of cervical cancer and to explore the influence of Foxp3 on the biological behaviors of cervical cancer cells. METHODS In this study, immunohistochemistry, lentivirus mediated transfection, Transwell assay; CCK-8 assay, real-time PCR and flow cytometry wer...

cervical and supraclavicular lymph nodes metastases generally arise from carcinomas of the head and neck. metastases to cervical lymph nodes from the prostate are very rare. the common site for lymph node metastasis from the prostate is infradiaphrag- matic. herein, we report a 69 year-old male who presented with cervical lymph node enlargement in the setting of prostate cancer. this type of pr...

PURPOSE Cervical cancer screening is an effective method for reducing the incidence and mortality of cervical cancer, but the screening attendance rate in developing countries is far from satisfactory, especially in rural areas. Wufeng is a region of high cervical cancer incidence in China. This study aimed to investigate the issues that concern cervical cancer and screening and the factors tha...

Background & aim: Pap smear is a screening procedure for cervical cancer. The incidence and mortality rate of cervical cancer has decreased up to 90% in the regular screening in women aged 20-65 years. This study aimed to investigate the Pap smear reports of pathology laboratories in Ahvaz, Iran. Methods: In this cross-sectional study, 1,006 Pap smear reports were collected from pathology labor...

results of the 53 neck dissection specimens, histopathology showed metastases in 16 cases. the overall accuracy of usgfna, us and palpation was 96%, 68% and 70%, respectively. the specificity of usgfna was superior to palpation and us alone. usgfna had the highest sensitivity, predictive value and accuracy in detecting cervical metastases compared with other performed tests. conclusion in our s...

Background: Updated information on the frequency of premalignant cervical lesions in Suriname is scant, while currently available data on the age and ethnic distribution of cervical dysplasia, cervical carcinoma, and cervical cancer deaths are inconsistent and conflicting. For these reasons, we assessed these topics using a retrospective cohort approach. Methods and Findings: Using secondary da...

With the introduction of cervical screening programs, the incidence and mortality of cervical cancer has been drastically reduced. Techniques such as the traditional Papanicolaou test and the newer liquid-based cytology allow for the early detection of cervical abnormalities prior to the development of invasive cervical cancer. As oncogenic human papillomavirus (HPV) infection is necessary for ...