The technically challenging field of single-molecule biophysics has established itself in the last decade by granting access to detailed information about the fate of individual biomolecules, unattainable in traditional biochemical assays. The appeal of single-molecules methods lies in the directness of the information obtained from individual biomolecules. Technological improvements in single-...

The highly successful architecture and supporting protocols of today’s Internet operate poorly when faced with operating environments such as very long delays, excessive loss, network partitioning, or short node lifetimes. Such properties are typically found in extreme environments which lack infrastructure or operate under severe constraints such as limited power. To achieve interoperability b...

iv List of Tables xi List of Figures xii Chapter

Female BALB/c mice were immunized intranasally with the mouse pneumonitis biovar of Chlamydia trachomatis and subsequently challenged in the ovarian bursa (C. trachomatis immunized, C. trachomatis challenged). Two groups of mice served as controls. One group was sham immunized intranasally with mock-infected HeLa 229 cell extracts and was challenged in the ovarian bursa with C. trachomatis MoPn...

CONGESTION CONTROL FOR NETWORKS IN CHALLENGED ENVIRONMENTS GUOHUA ZHANG, Ph.D. The University of Texas at Arlington, 2008 Supervising Professor: Yonghe Liu Congestion occurs when resource demands exceed the capacity of a network. The goal of congestion control is to use the network as efficiently as possible. While extensive efforts have been devoted to providing optimization based, distributed...

The answer to this question depends on how this emerging clinical research model challenges the standard expectations ethics has of clinical trials and whether ethics itself has to formulate a new critique to account for the novel aspects of phase 0 trials. In addition, providing an answer is a matter of some urgency because the expectation is that the number of phase 0 trials being conducted w...

Hemopure is purified haemoglobin in a sterile solution that acts as an oxygen bridge when compatible red blood cells are not readily available. It has been shown to save the lives of 42% of haemorrhaging and severely anaemic patients who would otherwise have died, and has no lasting sideeffects. The product is stable at room temperature, has a shelf life of 3 years and requires no blood cross-m...