The frequency of HAV, HBV, HCV and HDV infections were evaluated in children with thalassemia haematologic by ELİSA. A total 136 serum specimens tested for this purpose. Hepatitis B surface antigen (HBsAg) positivity was found 46 % patients leukemia, 50 lymphoma 16.6 thalassemic children. Anti present 8 leukeınia group group. our opinion, vira! hepatitis that have a great prevalence multitransf...

Iron deficiency anemia (IDA) and thalassemias are common diseases especially in the Mediterranean, Middle East and Asian regions. Both conditions show the same clinical findings of hypochromic and microcytic red blood cells. Although previous studies have devised mathematical formulae to differentiate between these two conditions, the prevalence of alpha- and beta-thalassemias among the affecte...

Haptoglobin (Hp) scavenges free hemoglobin following malaria-induced hemolysis. Few studies have investigated the relationship between the common Hp variants and the risk of severe malaria, and their results are inconclusive. We conducted a case-control study of 996 children with severe Plasmodium falciparum malaria and 1220 community controls and genotyped for Hp, hemoglobin (Hb) S heterozygot...

BACKGROUND Polypeptide hormone Leptin suppresses inflammation in the heart muscle and protects heart from diseases. The purpose of this study is to evaluate the relationship between leptin and troponin serum levels with cardiac involvement in patients with major beta thalassemia. MATERIALS AND METHODS In this cross-sectional study, 70 children with major thalassemia were selected. Two ml bloo...

AIM The aim of this study is to assess the growth parameters, vitamin D, calcium, and phosphorous status in children with thalassemia major receiving packed red cells transfusion with chelation therapy. PATIENTS AND METHODS In a case control study, 100 patients with beta thalassemia major (aged from 4 to 15 years) were compared with 100 sex- and age-matched children serves as a control group....

Background: Pain is described as the fifth vital sign, and inadequate pain management is linked to numerous immediate and long-term negative outcomes. Venipuncture is one of the most painful medical procedures in children. Distraction is one of the most effective ways to relieve pain. Reducing patients’ pain is important for all nurses for many reasons. Unnecessary pain can damage the nurse-...

Background: Retarded growth in thalassemic patient is complex and multi-factorial, it includes chronic hypoxia secondary to anemia when pre-transfusion haemoglobin below 9 g/dl. Development of sexual characteristics children markedly delayed as compared their non-thalassemic siblings the expected development criteria due iron overload. The main objective present study monitor these patients lon...

OBJECTIVE There are some reports in which a condition of zinc deficiency and its associated outcomes with a change in concentration of serum copper among the thalassemic patients has been highlighted. The aim of this prospective study was to determine the serum zinc and copper levels in children with beta-thalassemia major. METHODS In this cross sectional study all children under 12 years aff...

Pallor is deemed useful in the evaluation of patients suspected of anemia, although its perceived presence or absence may be misleading in cases with increased pigmentation with iron, melanin, or bilirubin. The purpose of this study was to determine the validity of pallor in the detection of anemia in children with beta-thalassemia as an iron overload model. Patients with beta-thalassemia A age...

OBJECTIVE To assess the effects of booklet and combining methods (lecture, video, etc.) on parents' awareness of children with beta-thalassemia major disorder. METHODS Two groups of parents (n=30 each) of children with thalassemia were selected randomly. Among educational programmes, in one group booklet and in the other group combined method were used. A questionnaire was designed to gather ...