OBJECTIVE Reactive arthritis (ReA) triggered by Chlamydia trachomatis or enteric bacteria such as yersinia, salmonella, Campylobacter jejuni, or shigella is an important differential diagnosis in patients presenting with the clinical picture of an undifferentiated oligoarthritis (UOA). This study was undertaken to evaluate the best diagnostic approach. PATIENTS AND METHODS 52 patients with Re...

A infeção por Chlamydia trachomatis é a sexualmente transmissível bacteriana mais comum no mundo. Habitualmente assintomática, mas pode conduzir graves consequências, em especial sexo feminino, como doença inflamatória pélvica, infertilidade, gravidez ectópica e dor pélvica crónica. prevalência global de 3,8% nas mulheres, sendo maioria dos casos entre os 15-24 anos. O diagnóstico feito com tes...

Waddlia chondrophila and Chlamydia trachomatis are intracellular bacteria associated with human miscarriage. We investigated their role in human preterm birth. Whereas presence of Chlamydia trachomatis DNA in genital tract was associated with human preterm birth, Waddlia was not, despite being present in women's genital tracts.

Effective adjuvants are needed to design effective vaccines against Chlamydia trachomatis (Ct). The aim of this study was to observe the immune response stimulated by inoculation of a DNA vaccine encoding a fusion protein comprising multiple Ct major outer membrane protein (MOMP) epitopes and human papillomavirus 6b L1 (HPV 6b L1) as the basis for designing a novel DNA vaccine against genital C...

Chlamydia trachomatis infection is a worldwide distributed sexually-transmitted infection that may lead to infertility. This study aims to report the prevalence of Chlamydia trachomatis infection among infertile women in Saudi Arabia. A community-based study, carried out at obstetrics and gynaecology clinic at Jazan General Hospital, Saudi Arabia. The study-group included 640 infertile women wh...

BACKGROUND Chlamydia trachomatis infection is a worldwide-distributed sexually transmitted infection that may lead to infertility. OBJECTIVES This study aims to report the prevalence of Chlamydia trachomatis infection among infertile women in Saudi Arabia. PATIENTS AND METHODS A community-based study carried out at the obstetrics and gynecology clinic at Jazan General Hospital, Saudi Arabia...

Chlamydia trachomatis, Ureaplasma urealyticum (T-mycoplasma), and Hemophilus vaginalis have previously been considered possible etiological agents in nongonococcal urethritis (NGU). In this study, current C. trachomatis infection was confirmed by culture and (or) micro-immunofluorescence serology in 26 of 69 men experiencing afirst episode of NGU, and 1 of 39 with no urethritis. Serum IgM immun...

Chlamydia trachomatis is an obligate intracellular bacterium that causes a variety of diseases in humans. C. trachomatis has a complex developmental cycle that depends on host cells for replication, during which gene expression is tightly regulated. Here we identify two C. trachomatis proteases that possess deubiquitinating and deneddylating activities. We have designated these proteins ChlaDub...

The Digene Hybrid Capture II (HCII CT/GC) test is a combination test designed to detect Chlamydia trachomatis and Neisseria gonorrhoeae in a single specimen. It is a nucleic acid hybridization test which uses signal amplification to increase sensitivity. We compared its performance to that of culture on cervical specimens from 1,370 women. Direct fluorescent-antibody assay was used to resolve d...

AIM The study tries to highlight the implication of CT infection in male infertility. MATERIAL AND METHODS There were 857 male patients enrolled in the study. The male cases have been investigated in the Gynecology and Urology Department of Ghencea Medical Center, Bucharest. All the selected cases have been done a spermogram test and for the diagnosis of the Chlamydia Trachomatis infection, t...