Movement disorders secondary to intrinsic spinal cord disease are rare. Paroxysmal chorea has not yet been reported in the neuromyelitis optica (NMO). We report a 43-year-old woman with relapsing-remitting cervical myelopathy who developed paroxysmal chorea during clinical exacerbation of NMO. MRI scan of the cervical spine revealed a long segmental enhancing lesion, but brain MRI did not show ...

A 45-year-old woman with an acquired multifocal neurologic syndrome, including chorea, dystonia, cerebellar dysfunction, multiple cranial neuropathies, and pure sensory neuropathy, was found at autopsy to have oat cell carcinoma. Neuropathologic examination revealed several features typically associated with remote effects of malignancy on the nervous system. We believe that this is the first d...

During a national investigation concerning all patients with Huntington's chorea in South Africa, 17 affected children, comprising 7 7% of the patients in the survey, were identified. Although the frequency of juvenile Huntington's chorea in the white community was equal to that reported from around the world, the frequency was much higher in the population ofmixed ancestry. It is possible that...

Systemic Lupus Erythematosus (SLE) is a disorder of the immune system with wide range symptoms. The involvement kidneys, lungs and central nervous (CNS) denotes more severe character worse prognosis. Several neurological psychiatric manifestations may be present, most common being convulsion, neuropathies acute confusional state, but chorea seen in less than 2% patients. Recent studies show tha...

ment, ' The treatment of chorea by large doses of arsenic was invented by an unqualified practitioner, who, on his death-bed, disclosed the secret of his success to Dr. Murray The secret was this : ' Fowler's solution, in 15 to 20 drops doses, might generally be given to children from 10 years old upwards for a few days without disturbing the stomach and that so given it was an almost infallibl...

Huntington's chorea is an hereditary disorder of the central nervous system characterized by the appearance in adult life of progressive chorea and dementia, and inherited in single autosomal dominant fashion with complete penetrance. The essential pathological features of Huntington's chorea are a primary loss of cells in the caudate nucleus and the putamen, and similar involvement of the cere...

An association exists between antiphospholipid antibodies and chorea. As these antibodies are associated with thrombosis, it has been suggested that cerebral infarction might cause chorea. However, CT and MRI typically do not demonstrate focal basal ganglionic lesions in such patients and an autoimmune mechanism for chorea has also been proposed. We report a young woman with left hemichorea and...

46% of sera from 30 children with rheumatic chorea showed IgG antibody reacting with neuronal cytoplasm of human caudate and subthalamic nuclei. The antibody was also detected in 14% of 50 children with active rheumatic carditis. 55 normal control sera, as well as 148 sera from a broad variety of other disease states showed a low prevalence (1.8-4.0%) of positive reactions. In rheumatic chorea ...