autism is a complex neuropsychiatric disorder that manifests in early childhood. although the etiology is unknown yet but, new hypothesis focused on identifying the key genes related to autism may elucidate its etiology. the main objective of the present study was to verify the value of karyotyping in autistic children and identifying association between chromosome abnormalities and autism.we e...

meiotic study was performed in 11 brassica napus cultivars considering chiasma frequency anddistribution, chromosome pairing, as well as the occurrence of b-chromosomes and their effects on chiasmafrequency. such cytogenetic pairing, along with agronomic characteristics, may be used in planninghybridization among the b. napus cultivars. all the cultivars studied possessed n=19 chromosome number...

Genetic aberrations are commonly seen in human preimplantation embryos. Non-disjunction and premature division of a chromosome are common in both meiosis and mitosis divisions. The expected result for meiotic aneuploidies is full aneuploidy in the later stages whereas mosaicism is the most frequent event in the cleavage and blastocyst stages. The main causes for mosaicism are post-zygotic event...

chromosome counting was performed in nine populations of achillea tenuifolia lam and eight populations of a. bieberestinii afan (asteraceae) collected from hamedan and kermanshah provinces in the west of iran. chromosome numbers in both species varied from 2n=2x=18 to 2n=4x=36. some populations of both species showed (2n=4x=36) chromosome number that is the first report as polyploidy levels. an...

background: high-energy ionizing radiation is harmful and changes the genetic makeup of dna, which can lead to increased risk of cancer. thus, the exposure of radiation dose should be under control and limited. ionizing radiation might lead to some chromosome aberrations like dicentric. there is a strong relation between the frequency of dicentric chromosome in metaphase, and the received dose....

Chromosome information is an important key for taxonomy, phylogeny and genetic in Trifolium plants. Thus, ten Trifolium species namely T. grandiflorum, T. resupinatum, T. dasyurum, T. campestre, T. tomentosum, T. hirtum, T. scabrum, T. lappaceum, T. stellatum, and T. repens were collected from their habitats in Fars province based on their morphologi...

Y chromosome microdeletions are the second genetic cause of male infertility. The incidence of Y chromosome microdeletions can vary considerably depending on several factors, including patient selection criteria, population composition, and diagnostic protocols. They are associated with spermatogenic failure and lead to azoospermia or oligozoospermia. The advance in assisted reproductive techno...

Background: Premature chromosome condensation (PCC) is a method for interphase chromosome analysis in biodosimetry. This study was performed to verify the usefulness of PCC induced by calyculin A in human peripheral blood lymphocytes (pbl) for biological dosimetry and possible construction of dose-response curve. Materials and Methods: Peripheral blood was obtained from a healthy donor and expo...

Propranolol (PL), a non-selective beta-blocker, is a cardiovascular drug widely used to treat hypertension. The present study was concerned with assessing the cytogenetic effects of this drug on Chinese hamster ovary (CHO) cell line. MTT assay was then carried out to determine the cytotoxicity index (IC50) of the drug. The IC50 value of PL was 0.43±0.02 mM. To investigate the clastogenic effect...

studies of postmeiotic chromosomes have been impeded by the thick exine of immature pollen grains. chromosome staining of immature and adult pollen grains through conven-tional acetocarmine procedure is tedious and often leads to unsatisfactory results. an acetocarmine stain, used in conjugation with carnoy’s solution as fixative for 72 hrs or until the chlorophyll-containing tissues of spike b...