OBJECTIVES A number of studies have shown that chronic hepatitis B virus infection is implicated in susceptibility to pancreatic cancer. However, the results are still controversial. This meta-analysis aimed to quantitatively assess the relationship between chronic hepatitis B virus infection and incidence of pancreatic cancer of cohort and case-control studies. METHODS A literature search wa...

در سالهای اخیر پیشرفتهای چشمگیری در تشخیص و درمان هپاتیت مزمن ب به دست آمده  و هر چند سال یک بار تغییر و تحولات قابل توجهی در نحوه درمان چنین بیمارانی به دنبال داشته است. اگرچه در چند سال اخیر راهنماهای درمانی متعددی برای هپاتیت مزمن ب در سطح دنیا ارائه شده است(5-1)، با گذشت زمان و انجام تحقیقات جدید، تفاوتهایی بین راهنماهای درمان قابل مشاهده می شود. علاوه بر این بسیاری از داروهای جدید قیمت بسی...

background and aims: many studies have provided evidence for the role of hepatitis b and c viruses in the development of liver cancer. although the routine treatment is available for both conditions, no definite guideline is available to treat patients dually infected with hbv and hcv. this study was performed to determine the frequency of hbv/hcv-coinfection in mashhad, north-east of iran. mat...

This study compared the response to adenine arabinoside 5'-monophosphate (ARA AMP) in 60 patients with chronic hepatitis B according to the pretreatment serum hepatitis B virus DNA concentration. The level of hepatitis B virus replication was defined as low (30 patients) or high (30 patients) when serum hepatitis B virus DNA concentration was below or above 100 pg/ml, respectively. Patients rec...

Correspondence to: Dr P Ferenci, Clinic of Internal Medicine IV, Department of Gastroenterology and Hepatology, University of Vienna, Wahringer Gurtel 18-20, A-1090 Wien, Austria. Abstract Interferon is currently considered to be the only accepted effective treatment for chronic viral hepatitis. A history of the treatment of chronic hepatitis B and C before the use of interferon is presented he...

Overview Pregnancy is generally considered to be an immunosuppressed state; however, the impact of pregnancy on mothers with viral hepatitis (Table 1) and the impact of viral hepatitis on fetuses/infants (Table 2) are not the same for all types of hepatitis. Pregnant women with acute hepatitis due to hepatitis E virus (HEV) or herpes simplex virus (HSV) have an increased risk of acute liver fai...

Interferon is currently considered to be the only accepted effective treatment for chronic viral hepatitis. A history of the treatment of chronic hepatitis B and C before the use of interferon is presented here. Hepatitis B virus does not seem to be directly cytopathic and the disease is known to be modulated largely by the host's immune response. Experience with immunosuppressant and immunosti...

Particles with properties similar to those associated with human hepatitis B were found in serum from woodchucks with chronic hepatitis and hepatocellular carcinoma. It is suggested that woodchuck hepatitis virus is a second member of a novel class of viruses represented by the human hepatitis B virus.

Viral hepatitis poses huge burden to the health care delivery system as well as to the economy of Bangladesh. Hepatitis E virus is the leading cause of acute hepatitis in this country, however with the improvement of economic status and sanitation this seems to be on the decline. Hepatitis B virus remains the leading cause in all forms of chronic liver diseases in this country. This virus has b...