Background: Chronic low back pain due to disc herniation is one of the common diseases in the community. In addition to the pain caused by this problem, which is a major complication, decreased and defective physical performance in daily living are other major concerns. Aim: To investigate the effect of combined therapeutic protocol (therapeutic exercises and massage) on the pain and physical p...

Introduction: When there is a pain requiring focused clinical attention and is associated with emotional and functional disorders, it is called pain disorder. The present study aims to study the role of selective attention, vigilance and ambivalence over emotional expressiveness for predicting pain severity in patients with chronic musculoskeletal pains. Methods: The study population included 1...

It has been reported that morphine tolerance does not develop in the presence of chronic pain. Therefore, this study was conducted to find out whether chronic inflammatory pain is able to eliminate or attenuate the developed tolerance to analgesic effect of morphine and also to investigate the role of lumbar spinal cord as a candidate site for this interaction. Tolerance was induced in adult ma...

Multiple sclerosis is a severe disorder of the central nervous system. This chronic and progressive disease involves unpredictable episodes of inflammatory attacks. It can cause functional limitations, disability and reduced quality of life. Pain is a common and significant problem in lots of people with multiple sclerosis (MS). And it is inversely correlated with aspects of life quality in ind...