This tale concentrates on a fatal affliction that has been permanently associated with human fate since time immemorial, well before Homo sapiens were even consciously aware of their existence. Incidentally, circulatory failure might have developed in the course of various severe diseases, cardiac defects, septic conditions, severe injuries; what is more – it could have been apparent in all age...

Surgical therapy for aortic arch disease involves partial or complete replacement of the aortic arch with reimplantation of the great vessels while the cerebral blood flow is temporarily altered. Patients undergoing this mandatory period of circulatory arrest during arch replacement are at an increased risk for adverse neurologic outcomes, and strategies for cerebral protection must be implemen...