Obvious decreasing in cervical cancer mortality has been observed in countries with organized cervical cancer screening programs [1]. Liquid based cytology is a technique that enables cells to be suspended in liquid medium and spread in monolayer for better morphological assessment. It includes the preparation and evaluation of cells collected in liquid fixative. It is being introduced to impro...

The suppressor of cytokine signalling (SOCS) gene family was originally identified as an immediate early response to cytokine signalling and function as negative regulators of the Janus kinase (JAK)/signal tranducers and activators of transcription (STAT) signal transduction pathway [Krebs and Hilton, J. Cell Sci. 113 (2000) 2813; Starr and Hilton, Int. J. Biochem. Cell Biol. 30 (1998) 1081]. A...

Various cytokines are involved in the regulation of the immune system and of hematopoiesis. Most cytokines utilize the so-called JAK-STAT pathway, but others activate the Ras-ERK pathway, which is more important than the STAT pathway for the proliferation of hematopoietic cells. Dysregulation of cytokine signaling can cause a variety of diseases, including allergy, inflammation, and cancer. We ...