Helicobacter pylori is a gastric pathogen that causes several gastroduodenal disorders such as peptic ulcer disease and gastric cancer.  Eradication efforts of H. pylori are often hampered by antimicrobial resistance in many countries, including Vietnam.  Here, the study aimed to investigate the occurrence of antimicrobial resistance among H. pylori clinical isolates across 13 hospitals in Viet...

OBJECTIVE To determine whether treatment with clarithromycin for respiratory tract infections was associated with an increased risk of cardiovascular (CV) events, arrhythmias or all-cause mortality compared with other antibiotics. DESIGN Retrospective cohort design comparing clarithromycin monotherapy for lower (LRTI) or upper respiratory tract infection (URTI) with other antibiotic monothera...

AIM Most patients treated for H. pylori infection receive empirical therapy based on epidemiological data of antibiotic resistance. However, previous European studies indicate that resistance patterns may be changing. Therefore, the aim of this study was to investigate the prevalence of primary clarithromycin and/or metronidazole resistant H. pylori strains over a six-year period (1997-2002) in...

PURPOSE Clarithromycin was considered the cornerstone for the treatment of Mycobacterium abscessus complex infections. Genetic resistance mechanisms have been described and many experts propose amikacin as an alternative. Nevertheless, clarithromycin has several advantages; therefore, it is necessary to identify the non-functional erm(41) allele to determine the most suitable treatment. The aim...

BACKGROUND Clarithromycin is a macrolide antibiotic that possesses anti-inflammatory and immunomodulatory properties. Although recent data suggests that macrolide antibiotics enhance Pseudomonas aeruginosa clearance from the lung, involving natural killer (NK) T cells in this process by activating the NKG2D-NKG2D ligand system, the precise underlying mechanism is still unclear. In this study, w...

objective(s)cutaneous leishmaniasis is a common parasitic disease which is endemic in some parts of the world. in vitro and in vivo studies have shown azithromycin efficacy on some leishmania species. because of structural similarity between clarithromycin and azithromycin and efficacy of clarithromycin against intracellular organisms and due to the absence of previous studies in this respect, ...

although several treatments have been suggested for nasal polyposis, from medical to surgical, there is no standard guideline for the management of this disease. during recent years increasing attention has been directed toward the effects of macrolide antibiotics on chronic sinusitis and nasal polyposis. in this study,  the efficacy of clarithromycin on severe nasal polyposis were examined. in...

the aim of this study was to determine the resistance rates of helicobacter pylori (h. pylori) to various antimicrobial agents. the agar disk diffusion method (kirby bauer) was used to determine the sensitivity of h. pylori isolates to various antimicrobials. of the 61 h. pylori isolatestested, no isolates was resistant to amoxycillin and tetracycline. the resistance rates were 42.6% for metron...

background: helicobacter pylori (h. pylori) resistance to antibiotics has become a global problem and is an important factor in determining the outcome of treatment of infected patients. the purpose of this study was to determine the h. pylori resistance to clarithromycin, metronidazole, and amoxicillin in gastrointestinal disorders patients. materials and methods: in this study, a total of 260...

The term 'antibiomania' refers to manic episodes that occur after a patient starts taking antibiotics. We report the case of a 49-year-old male who developed acute psychosis secondary to initiation of triple therapy for Helicobacter pylori eradication. Unlike with proton pump inhibitors, there have been several reported cases of central nervous system side effects and psychiatric consequences d...