The immune response involves the generation of Ab-secreting cells and memory B cells through a process called terminal B lymphocyte differentiation. This program requires the transcriptional repressor Blimp-1, which inhibits c-myc expression and terminates proliferation. Although the role of c-Myc in cell proliferation is well characterized, it is not known whether it has other functions in ter...

A rail-to-rail class-AB CMOS buffer is proposed in this paper to drive large capacitive loads. A new technique is used to reduce the leakage power of class-AB CMOS buffer circuits without affecting dynamic power dissipation .The name of applied technique is LECTOR, which gives the high speed buffer with the reduced low power dissipation (1.05%) and reduced area (2.8%). The proposed buffer is si...

This paper describes a CMOS analogy voltage supper buffer designed to have extremely low static current Consumption as well as high current drive capability. A new technique is used to reduce the leakage power of class-AB CMOS buffer circuits without affecting dynamic power dissipation. The name of applied technique is TRANSISTOR GATING TECHNIQUE, which gives the high speed buffer with the redu...

BACKGROUND AND PURPOSE Red wine polyphenols (RWPs) inhibit the expression of vascular endothelial growth factor (VEGF), a major pro-angiogenic and pro-atherosclerotic factor, in vascular smooth muscle cells (VSMCs). The aim of this study was to identify which red wine polyphenols were inhibitory and to determine the mechanism underlying the inhibitory effects. EXPERIMENTAL APPROACH Release of...

BACKGROUND The aim of this study was to explore the effects of HCV co-infection on virological effectiveness and on CD4+ T-cell recovery in patients with an early and sustained virological response after HAART. METHODS We performed a longitudinal analysis of 3,262 patients from the MASTER cohort, who started HAART from 2000 to 2008. Patients were stratified into 6 groups by HCV status and typ...

When two targets are presented in rapid succession, perception of the second target is impaired at short intertarget lags (100-700 msec). This attentional blink (AB) is thought to occur only when the second target is backward masked. To the contrary, we show that task switching between the targets can produce an AB even without masking (Experiments 1 and 3). Further, we show that task switching...

The roles of mutational and recombinational processes in the diversification of the exon encoding the antigen binding site in the murine major histocompatibility complex class II gene Ab were assessed by phylogenetic analysis of allelic nucleotide sequences. A total of 46 alleles of Ab exon 2 from 12 Mus species or subspecies and 2 Rattus species were sequenced after amplification by the polyme...

A fully integrated differential class-AB power amplifier has been designed in a 0.25um CMOS technology. It is intended for medium output power ranges such as Bluetooth class I, and has an operating frequency of 2.45GHz. By using two parallel output stages that can he switched on or off, a high efficiency can be achieved for both high and low output power levels. The simulated maximum output pow...

The growth of in-car entertainment systems demands smart power devices, including audio power amplifiers. Despite the trend towards class-D systems, integrated class-AB amplifiers are still superior in terms of frequency response, integration level and ease of application. The market drive for lower distortion and higher stability demands good frequency compensation schemes. Still, to the best ...