A large, population-based case-control study of facial clefts was carried out in Norway between 1996 and 2001. The study included 573 cases -- 377 with cleft lip with or without cleft palate and 196 with cleft palate only -- and 763 randomly selected controls. Maternal consumption of coffee and other caffeine-containing beverages in early pregnancy was recorded shortly after birth. Compared wit...

OBJECTIVES Determination of the psychosocial status and assessment of the level of satisfaction in Malaysian cleft palate patients and their parents. DESIGN Cross-sectional study. PARTICIPANTS AND METHODS Sixty cleft lip and palate patients (12 to 17 years of age) from Hospital Universiti Sains Malaysia and their parents were selected. The questionnaires used were the Child Interview Schedu...

In a search for genetic differences in susceptibility to cleft palate, congenic and recombinant inbred strains of mice were treated with 6-aminonicotinamide or control injections. Of six loci tested, only the chromosome segment marked by N-acetyl transferase was found to affect susceptibility to 6-aminonicotinamide-induced cleft palate. This chromosome segment is known to affect glucocorticoid-...

UNLABELLED Cleft lip and/or palate (CL/P) represent the most common congenital anomalies of the face, corresponding to approximately 65% of all malformations of the craniofacial region. AIM to describe unusual clinical cases of non-syndromic CL/P (CL/PNS), diagnosed in a reference service in Minas Gerais, Brazil, and correlate these alterations with possible risk factors. MATERIALS AND METH...

Airway management in cleft lip and palate surgery Cleft lip and palate are the most common of the craniofacial anomalies, with an incidence of approximately 1 in 800 live births. Twenty-five percent of cases of cleft lip are bilateral, and 85 % of these are associated with cleft palate. In recent years there has been a move towards earlier surgical repair of both cleft lip and palate, with clef...

OBJECTIVE In patients with cleft lip and palate, the aims of this study were to generate objective measures of different attributes of lip movement and to explore the utility of these objective measures by examining the association between examiners' subjective assessments with the objective measures. PATIENTS AND PARTICIPANTS Thirteen patients with unilateral cleft lip and palate with varyin...

Cleft is a congenital abnormal space or gap in the upper lip, alveolus, palate. This abnormality occurs between 5th and 10th weeks of pregnancy. Clefts are divided into cleft palate, as well lip palate caused by interaction individual genes with certain environmental factors. Mothers’ knowledge about risk factor may promote better health-related behavior their pregnancy increasing understanding...

Outgrowth and fusion of the lateral and medial nasal processes and of the maxillary process of the first branchial arch are integral to lip and primary palate development. Wnt9b mutations are associated with cleft lip and cleft palate in mice; however, the cause of these defects remains unknown. Here, we report that Wnt9b(-/-) mice show significantly retarded outgrowth of the nasal and maxillar...

A child born with cleft lip and palate may experience difficulties while feeding. Obtaining a good seal of the oral cavity can be difficult due to the incomplete facial and palatal structures. Nasal regurgitation and choking are common in infants with cleft palate because of inability of the palate to separate the nasal and oral cavities. The case presented here is a 3-day-old neonate born with...

The results of previous epidemiologic research on the possible association between maternal smoking during pregnancy and risk of oral clefts in offspring have been inconsistent. This may be due in part to methodological limitations, including imprecise measurement of tobacco use, failure to consider etiologic heterogeneity among types of oral clefts, and confounding. This analysis, based on a l...