BACKGROUND Although intravitreal injection of bevacizumab (IVB) is effective for macular edema in patients with branch retinal vein occlusion (BRVO), the changes of retinal hemodynamics remain unclear. We investigated retinal hemodynamic changes in BRVO patients after IVB by performing laser speckle flowgraphy (LSFG). METHODS In 35 BRVO patients with macular edema, the relative flow volume (R...

BACKGROUND The association of inflammatory factors and the aqueous flare value with macular edema in central retinal vein occlusion (CRVO) patients remains unclear. We investigated the relations between the aqueous flare value and vitreous levels of vascular endothelial growth factor (VEGF), soluble intercellular adhesion molecule-1 (sICAM-1), and interleukin-6 (IL-6) in patients with CRVO and ...

BACKGROUND To investigate the efficacy of posterior subtenon methylprednisolone acetate injection in treatment of refractory diffuse clinically significant diabetic macular edema (CSME). METHODS In a prospective, nonrandomized, interventional case series, 52 eyes were diagnosed with CSME and treated with at least two sessions of laser photocoagulation according to Early Treatment Diabetic Ret...

Purpose: We evaluated the macular, functional and structural features of patients with retinal vein occlusion macular edema. measured best-corrected visual acuity (BCVA), central foveal thickness, area avascular zone after intravitreal bevacizumab (IVB) treatment placement a dexamethasone implant (IVD).Methods: retrospectively reviewed 36 eyes edema who underwent IVB (20 eyes) IVD (16 eyes). Th...

PURPOSE To determine the incidence of rebound macular edema after intravitreal bevacizumab in eyes with macular edema secondary to branch retinal vein occlusion and to identify the pretreatment factors that were significantly associated with the rebound. METHODS The changes in the foveal thickness after the intravitreal bevacizumab (1.25 mg/0.05 mL) were studied in 65 eyes of 65 patients with...

PURPOSE Diabetic macular edema can be refractory to multiple treatment modalities. Although there have been anecdotal reports of ranibizumab showing efficacy when other modalities provided limited benefit, little has been published on treatment for refractory diabetic macular edema. This study sought to investigate this observation further. METHODS Retrospective chart review. RESULTS Thirty...

BACKGROUND To investigate the effects of dyslipidemia and statin therapy on progression of diabetic retinopathy and diabetic macular edema in patients with type 2 diabetes. METHODS The medical records of 110 patients with type 2 diabetes (70 statin users and 40 non-users) were retrospectively reviewed. The two outcome measures were progression of diabetic retinopathy by two or more steps on t...

The purpose of the study was to compare the effectiveness of intravitreal injection of tissue plasminogen activator and avastin with avastin on macular thickening and visual acuity in macular edema due to branch Retinal Vein Occlusion (BRVO) that had not received any treatment. In this double-blind randomized controlled trial, Fifty eyes of 50 patients with macular edema because of BRVO were ra...

diabetic retinopathy is the leading cause of blindness in the world. strict control of blood sugar, blood pressure, laser therapy, pharmacotherapy and vitrectomy are of among common diabetic retinopathy treatments. further studies to investigate the effect of protein kinase c inhibitors, angiotensin converting enzyme inhibitors, growth hormone and other proposed treatments for diabetic retinopa...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : diabetic macular edema (dme) is the most common cause of reduced vision in diabetic patients. with regards to its prevalence and its severe morbidity, attention to new methods of treatment like anti-vascular endothelial growth factor (vegf) therapy is of great importance. therefore, this study aimed to evaluat...