نتایج جستجو برای: cmv antibody
تعداد نتایج: 173750 فیلتر نتایج به سال:
A monoclonal antibody was used to detect an early antigen of cytomegalovirus (CMV) by fluorescence 16 h after inoculation of MRC-5 monolayers in 1-dram (ca. 3.7-ml) shell vials and low-speed centrifugation. Of 770 specimens (urine, blood, lung tissue, sputum) processed in shell vials, 124 (16%) were positive for the virus at 16 h postinfection. CMV was isolated in standard tube cell cultures (a...
Anti-human cytomegalovirus (CMV) monoclonal antibody (MAb) F6b produced by clone 95/12 was used for the rapid diagnosis (16 to 24 h) of CMV isolates in 308 clinical specimens and compared with classic isolation. MAb F6b gave 100% correlation with isolation. When this MAb was used for direct diagnosis with 212 urine and bronchoalveolar specimens, detection of CMV varied from 50 to 75% compared w...
Background Many reports have described the development of bullous pemphigoid (BP) following COVID-19 vaccination. In dipeptidyl peptidase-4 inhibitor-associated BP (DPP-4i-BP), cessation DPP-4i appears to a paradoxical effect on clinical course BP. Interestingly, similar reactions been shown develop after antibody-based therapies that inhibit pro-inflammatory cytokine signalling. These heteroge...
Abstract Human cytomegalovirus (CMV) is a contributing factor to tumour expansion and progression in glioblastoma patients. Patient-derived non-modified CMV-specific T cells can be isolated, ex vivo re-stimulated with CMV expanded before IV infusion. Adoptive cell Therapy has been shown improve GBM prognosis. We aimed develop protocol. PBMCs were isolated from blood of 12 healthy CMV-antibody p...
This study evaluate the potential of plasmatic CXCL-10 (pCXCL-10) as a pre&post transplantation prognostic and diagnostic biomarker T-cell-mediated rejection (TCMR), antibody-mediated (ABMR) subclinical (SCR) risk in adult kidney recipients considering BKV CMV infections possible clinical confounder factors. Twenty-eight 100 patients included experienced (TCMR:14; ABMR:14); 8 SCR; 13 16 were di...
By using dram vial cell culture methods, three commercially available tests for cytomegalovirus (CMV) detection were compared: direct fluorescent monoclonal antibody staining for CMV-specific early and late antigens (direct FA), indirect fluorescent monoclonal antibody staining for a CMV-specific early antigen (indirect FA), and in situ DNA hybridization with a biotinylated CMV-specific DNA pro...
Interest in transfusion-associated Cytomegalovirus (CMV) infections began with the recognition that the overwhelming majority of cases of late-onset postperfusion mononucleosis were heterophile negative (1, 2). In 1965 Klemola and Kaariainen (3) associated heterophile-negative mononucleosis with CMV infection, and 1 year later the same group documented the association ofCMV infection with heter...
A new microparticle enzyme immunoassay (MEIA), the Cytomegalovirus (CMV) Immunoglobulin M (IgM) test, was developed on the Abbott AxSYM analyzer. This test uses recombinant CMV antigens derived from portions of four structural and nonstructural proteins of CMV: pUL32 (pp150), pUL44 (pp52), pUL83 (pp65), and pUL80a (pp38). A total of 1, 608 specimens from random volunteer blood donors (n = 300),...
Despite the rapid advance in the understanding of molecular pathways underlying human colorectal tumorigenesis, the causes that initiate dysregulation of the pathways remain largely unknown. Human cytomegalovirus (CMV) has been implicated as a potential etiopathogenetic agent. To further investigate whether CMV participates in human colorectal tumorigenesis, we examined 23 colorectal hyperplast...
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