Preformulation studies on transdermal dosage forms involve liberal use of animal skin for assessing the permeation characteristics of drugs, influence of permeation enhancers, optimizing the formulation variables etc. The restricted availability of animal skin due to concerns regarding prevention of cruelty to animals has generated considerable interest in developing polymeric films for use as ...

Preformulation studies on transdermal dosage forms involve liberal use of animal skin for assessing the permeation characteristics of drugs, influence of permeation enhancers, optimizing the formulation variables etc. The restricted availability of animal skin due to concerns regarding prevention of cruelty to animals has generated considerable interest in developing polymeric films for use as ...

OBJECTIVES The purpose of this study was to investigate the permeation of the low-volatile solvent limonene through different disposable, unlined, unsupported, nitrile exam whole gloves (blue, purple, sterling, and lavender, from Kimberly-Clark). METHODS This study utilized a moving and static dextrous robot hand as part of a novel dynamic permeation system that allowed sampling at specific t...

Amorphous glassy perfluorinated polymers have high gas permeability, are chemically inert, thermally stable and known for their superior separation performance several pairs. In the current study, of copolymers perfluoro(butenyl vinyl ether) (PBVE) perfluoro(2,2-dimethyl-1,3-dioxole) (PDD) with two different monomer ratios, commercially as CyclAFlor™, was studied first time, both at 35 °C highe...

1387-1811/$ see front matter 2012 Elsevier Inc. A http://dx.doi.org/10.1016/j.micromeso.2012.03.052 ⇑ Corresponding authors. E-mail addresses: [email protected] (C.W. Jo ch.edu (S. Nair). The effect of typical membrane processing conditions on the structure, interfacial morphology, and gas separation performance of MOF/polymer nanocomposite membranes is investigated. In particular, the ZIF...

Two multicomponent models for spiral-wound gas permeators are proposed. The basic transport model is derived from fundamental material balances and permeation relations that account for permeate-side pressure variations. The resulting model consists of a set of nonlinear differential-algebraic-integral equations with mixed boundary conditions, as well as an implicit expression for the local fee...

OBJECTIVES Microvascular invasion and microlymphatic permeation are indicators of microscopic tumour invasion into small vessels and have been considered to be powerful prognostic indicators for non-small-cell lung cancer (NSCLC). Several studies have suggested that these should be included in the TNM classification, but, there have been conflicting results regarding the prognostic impact of mi...

The present work reports on the gas transport behavior of mixed matrix membranes (MMM) which were prepared from multi-walled carbon nanotubes (MWCNTs) and dispersed within polymers of intrinsic microporosity (PIM-1) matrix. The MWCNTs were chemically functionalized with poly(ethylene glycol) (PEG) for a better dispersion in the polymer matrix. MMM-incorporating functionalized MWCNTs (f-MWCNTs) ...

Microporous silica materials with a controlled pore size and a narrow pore size distribution have been prepared by sol-gel processing using an organic-templating approach. Microporous networks were formed by pyrolytic removal of organic ligands (methacryloxypropyl groups) from organic/inorganic hybrid materials synthesized by copolymerization of 3-methacryloxypropylsilane (MPS) and tetraethoxys...