Menorrhagia is a common gynecological symptom. In adolescents, the cause is generally dysfunctional uterine bleeding. Menorrhagia may also be due to undiagnosed coagulation defects, endocrine disorders, gynecological abnormalities of the uterus, or other systemic disorders. Menorrhagia may be the only clinical manifestation of an inherited bleeding disorder. We report a case of inherited hypopr...

Conditions which interfere with coagulation may increase the risk of post-procedural bleeding and/or complications during interventional radiology procedures. This study investigates influence disorders on acute post-operative outcomes following lower extremity endovascular interventions for peripheral arterial disease (PAD). The 2014 to 2017 American College Surgeon’s National Surgical Quality...

Background Bone marrow transplantation (BMT)is nowadays used in various hematological disorders including leukemias. Hemophilia A & B are sex linked bleeding disorders in which there are various genetic abnormalities in factor VIII & IX genes. Among various hematological disorders, bleeding disorders mainly hemophilia in now widely treated using plasma derived and recombinant factor VIII & IX ...

Background It has been reported that 15-20% of parous female have experienced at least one miscarriage, while 3% of them have experienced two miscarriages. The goal of this study was to evaluate the plasma level of coagulation factors in women with a history of spontaneous abortions. MaterialsAndMethods In this case-control study, 82 women with a history of two or more abortions referred to the...

We report a case of patient with recurrent hematomas while on anticoagulation for pulmonary embolism and prolonged hospital stay due to delayed diagnosis acquired hemophilia A. Acquired A is rare autoimmune bleeding disorder autoantibodies directed against coagulation factor VIII (FVIII), leading an FVIII deficiency. isolated activated partial thromboplastin time (aPTT) in warrants workup This ...

Background: Bleeding assessment tools are key components in the evaluation of patients suspicious for bleeding disorders. The exact determination of the normal ranges of ISTH-BAT (International Society on Thrombosis and Hemostasis –Bleeding Assessment Tool) in the healthy population is a crucial step for determining who needs to be referred for further coagulation laboratory examinations. We ai...