Renal impairment has already been cited as being under-reported. A retrospective cross-sectional study was carried out. The sample population consisted of 94 inpatients aged over 60 years at Clayponds Hospital in the UK who had been admitted for rehabilitation from acute hospitals. The glomerular filtration rate (GFR) was calculated using the Cockcroft-Gault formula modified for SI units. Renal...

Regarding the prevalence of chronic kidney disease in the population, estimation of glomerular filtration rate is of importance. Creatinine-based formulas are thus useful as the first step of a prevention strategy. Several creatinine-based formulas have been published. Among these, the Cockcroft-Gault formula and the Modification of Diet in Renal Disease (MDRD) study equation are the most used ...

BACKGROUND Renal function is an important prescribing consideration. On average, glomerular filtration rate declines by about 10 mL/min every 10 years after the age of 40. Renal impairment may cause medicines to accumulate or cause toxicity, especially if the medicine has a narrow therapeutic index. OBJECTIVE To present an overview of prescribing considerations in the primary care setting for...

Glomerular filtration rate (GFR) is considered as the best way to assess global renal function (Gaspari et al., 1997; Stevens & Levey, 2009). Even if GFR estimations (based on creatinineor cystatin C-based equations) are most often used (see Table 1)(Cockcroft & Gault, 1976; Levey et al., 1999; Levey et al., 2006; Levey et al., 2009), measuring “true” GFR is still important in clinical practice...

La détermination du Débit de Filtration Glomérulaire (DFG) est importante chez les drépanocytaires fait qu’ils constituent un groupe patients lesquels des atteintes rénales sont fréquemment décrites notamment l’hyperfiltration glomérulaire. Dès lors, à une époque où calculateurs en ligne proposent simultanément différentes formules DFG, il serait important d’évaluer au sein d’une population noi...

Clinical guidelines suggest neoadjuvant cisplatin-based chemotherapy prior to cystectomy in the setting of muscle-invasive bladder cancer (MIBC). A creatinine clearance (CrCl) >60 mL/min is frequently used to characterize cisplatin-eligible patients, and use of the CKD-EPI equation to estimate CrCl has been advocated. From a prospectively maintained institutional database, patients with MIBC wh...

CAPD patients given lercanidipine developed non-infective turbid peritoneal dialysis. Differential diagnosis of non-infectious cloudy peritoneal dialysate includes cellular causes (i.e. leucocyte, eosinophils, red cells and malign cells) and non-cellular causes (i.e. triglyceride and drugs) [2]. Yoshimoto et al. [1,3] reported that benidipine, manidipine, nisoldipine and nifedipine caused cloud...