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conclusions baseline characteristics can inform who is at higher risk of renal disease mortality over the next 25 years. race, age, drinking, smoking, hypertension, and diabetes at baseline can all inform programs to reduce burden of kidney disease. results in multivariable model, race, age, drinking, smoking, hypertension, and diabetes at baseline predicted deaths due to renal disease. gender,...

conclusions these findings indicated the association of the hbsag titer and serum ifnar2 in hbsag clearance in hepatitis b virus- infected patients. in consequence, immune mechanisms related to ifn-α/β signaling might be responsible in chb outcome. background loss of hepatitis b surface antigen (hbsag) in chronic hepatitis b (chb) infection is a favorable outcome. type i interferon (ifni) has a...

conclusions ap did not prevent utis and resulted in more resistant organisms requiring iv antibiotics. discontinuing ap allowed the return of susceptibility to oral antimicrobials and significantly improved gfr in those children who had previously been on ap. adherence to a catheterization regimen with prompt treatment of symptomatic uti conserved renal function and prevented selection of resis...

the purpose of this paper is to investigate the differences in value of children between the 1960s, 1970s, after 1980 birth cohort, and identifying the factors affecting. the data for this study are drawn from a survey in semnan province in 2012. information is related to 405 married women aged 15-49 years. the result shows that the highest score of the children value belonged to the 1960 birth...

Recent cohort studies have relied on exposure prediction models to estimate individuallevel air pollution concentrations because individual air pollution measurements are not available for cohort locations. For such prediction models, geographic variables related to pollution sources are important inputs. We demonstrated the computation process of geographic variables mostly recorded in 2010 at...

Microevolutionary projections use empirical estimates of genetic covariation between physical or psychological phenotypes and reproductive success to forecast changes in the population distributions of those phenotypes over time. The validity of these projections depends on relatively consistent heritabilities of fertility-relevant outcomes and consistent genetic covariation between fertility a...

BACKGROUND Asthma is a heterogeneous condition and differential effects of pet ownership on non-atopic versus atopic asthma have been reported. The aim of this study was to investigate whether pet ownership during pregnancy and early childhood was associated with wheezing from birth to age 7 years and with lung function at age 8 years in a UK population-based birth cohort. METHODS Data from t...

Obesity is considered a public health problem worldwide. Evidence from epidemiologic studies has shown that early undernutrition may be a determinant of obesity later in life. Longitudinal studies are scarce in the setting of low- and middle-income countries. In Pelotas, southern Brazil, a birth cohort has been followed since 1982. Between 2004 and 2005, 4297 members of this cohort were intervi...

We conducted high-dimensional propensity score-adjusted cohort studies to examine whether thiazolidinedione use with a statin or fibrate was associated with an increased risk of severe hypoglycemia. We found that concomitant therapy with a thiazolidinedione+fibrate was associated with a generally delayed increased risk of severe hypoglycemia.