نتایج جستجو برای: collagen cross
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We investigated attachment and migration of human retinal pigment epithelial cells (primary, SV40-transfected and ARPE-19) on nanoscopically defined, two-dimensional matrices composed of parallel-aligned collagen type I fibrils. These matrices were used non-cross-linked (native) or after riboflavin/UV-A cross-linking to study cell attachment and migration by time-lapse video microscopy. Express...
The neutral salt-soluble collagen which accumulates in the tissues of animals treated with penicillamine does not differ from normal in amino acid composition, specific optical rotation, and melting temperature. It has higher intrinsic viscosity, possibly due to a contamination with higher molecular weight aggregates originating from the depolymerization of insoluble collagen. In contrast to th...
Because of its dynamic nature, the composition and structure of the myocardial collagen network can be reversibly modified to adapt to transient cardiac injuries. In response to persistent injury, however, irreversible, maladaptive changes of the network occur leading to fibrosis, mostly characterized by the excessive interstitial and perivascular deposition of collagen types I and III fibers. ...
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