The flow and transport of solute molecules in the intricate structure placenta make organ a fetal life-support system.

Cholinesterases are measured to assess exposures to or effects of organophosphorus esters and carbamates. Plasma butyrylcholinesterase is usually most sensitive to inhibitors, but it has no known physiological function(s); its inhibition reflects exposure. The physiological function of erythrocyte acetylcholinesterase (AChE) also is not known, but the enzyme is the same as that involved in syna...

When (if ever) a judicial action can be an unconstitutional taking of private property has long been an open question in American constitutional law. Nested within this larger question are a host of detailed issues concerning both substance and procedure. Despite passing references in some cases, and a more direct discussion in one concurring opinion, the Supreme Court of the United States—unti...

Evidence exists for the potential protective effects of circulating ovarian hormones in stroke, and oestrogen reduces brain damage in animal ischaemia models. However, a recent clinical trial indicated that HRT (hormone-replacement therapy) increased the incidence of stroke in post-menopausal women, and detrimental effects of oestrogen on stroke outcome have been identified in a meta-analysis o...

Executive Summary The purpose of this white paper is educational. It is designed to impart a better understanding of what is meant by the term comparative effectiveness and to communicate the complexities that surround it. The primary purpose of comparative effectiveness research is to inform healthcare related decisions. While comparative effectiveness can be a valuable tool to inform the deci...

A function f : V → {−1, 0, 1} is a minus-domination function of a graph G = (V,E) if the values over the vertices in each closed neighborhood sum to a positive number. The weight of f is the sum of f(x) over all vertices x ∈ V. The minus-domination number γ(G) is the minimum weight over all minus-domination functions. The size of a minus domination is the number of vertices that are assigned 1....