Cerebral malaria is a severe manifestation of a parasitic infection caused by Plasmodium falciparum. The sequelae of this disease such as blindness, deafness, loss of motor function could be emotionally traumatic and physically disabling. We, therefore, present this case of an 8-year-old boy who presented with high-grade intermittent fever associated with multiple convulsions and prolonged coma...

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 33-year-old man presented with left hypochondrium pain and high-grade fever for 1 week and generalized convulsions followed by persistent unconsciousness. 2.8 mg/dL. His coagulation profile showed an international normalized ratio of 2.4, along with severe...

Plasmodium falciparum is known for complications with a very high mortality. We report three cases in children of the same family, two of them developed ARDS, one of them died, the third child developed hemophagocytosis and one of them also had transient myocarditis, all unusual complications of falciparum malaria.

Severe malaria is a medical emergency that requires urgent recognition and treatment, because it may rapidly progress to serious complications and death. We report a case of imported severe malaria tropica in an adult traveller, with a parasitemia of 20%, complicated by acute renal failure. Patient was initially misdiagnosed by a physician unaware of the importance of patients travel history, a...

prophylaxis were 34.6% (n=35), while the rest were on no prophylaxis. Complicated cases were: 5 cases presented with cerebral malaria, one of them succumbed while the rest recovered completely; 4 presented with uremia and were referred for dialysis, one of them passed away after the first dialysis session. Other clinical presentations were seen such as: upper gastro-intestinal bleeding, diarrhe...

Malaria is a devastating and complicated disease caused by the Plasmodium parasite. P. falciparum has developed a mechanism for evasion of immune responses and clearance from the blood stream by adhering to endothelial cells in different organs. This is achieved by the expression of P. falciparum erythrocyte membrane protein 1 (PfEMP1) proteins on the surface of infected red blood cells (iRBCs)...