This study reports the first measurements of sulphur and boron isotopic compositions in olivine-hosted melt inclusions (MI) from basaltic lava scoria deposits 1941 Tolbachik eruption, Kamchatka, Russia. The primary aim present is to constrain origin relation silicate-sulphide immiscibility that occurred mafic magmas. Melt fall into two compositionally distinct groups based on their S- B-isotope...

Inhibition of the cyclin dependent kinase 2 (CDK2) is a well-known cancer treatment approach. Based on molecular docking simulation analysis, two new series 2-(1-(4-methoxyphenyl)-2-(phenylsulfonyl)ethylidene)hydrazineylidene)-2,5-dihydrothiazole as CDK-2 inhibitors were designed. The lead compound IV (5-benzoyl-N2-phenyl-1,3-thiazole-2,4-diamine) was modified and optimized prior to this analys...

dft calculations were applied to evaluate the electronic and magnetic properties of zigzag bc2nnanotubes based on the 13c, 15n, and 11b nmr parameters and natural charge analysis. weconsidered three types of zigzag nanotubes, zz-1, zz-2, and zz-3 (n, 0) with n = 8, 12, and 14. theobtained results indicated the divisions of the electrostatic environments around c nuclei into a fewlayers, consist...

Methionine restriction (MR) limits age-related adiposity in Fischer 344 (F344) rats. To assess the mechanism of adiposity resistance, the effect of MR on adipose tissue (AT) 11b-hydroxysteroid dehydrogenase-1 (11bHSD1) was examined. MR induced 11b-HSD1 activity in all ATs, correlating with increased tissue corticosterone. However, an inverse relationship between 11b-HSD1 activity and adipocyte ...

1 State Key Laboratory of Soil Erosion and Dryland Farming on the Loess Plateau, Institute of Soil and Water Conservation, Chinese Academy of Sciences, Yangling 712100, China 2 College of Urban and Environmental Sciences, Northwest University, Xi’an 710027, China; E-Mails: [email protected] (X.Y.); [email protected] (J.Z.); [email protected] (Y.L.); [email protected] (Y.Z.); zha...