Sensory and social deprivation from the mother and littermates during early life disturbs the development of the central nervous system, but little is known about its effect on the development of the peripheral nervous system. To assess peripheral effects of early isolation, male rat pups were reared artificially in complete social isolation (AR); reared artificially with two same-age conspecif...

The complex interactions among the structural features of axon, its myelin sheath and its length, determine the nature of nerve impulse conduction.. In addition, fibers of different diameters and degree of myelination determine the nerve conduction velocity (NCV). It is therefore, hypothesized that for the same nerve, the NCV may differ in animals, due to the differences in the leg architecture...

OBJECTIVE Interruption of energy supply to peripheral axons is a cause of axon loss. We determined whether glycogen was present in mammalian peripheral nerve, and whether it supported axon conduction during aglycemia. METHODS We used biochemical assay and electron microscopy to determine the presence of glycogen, and electrophysiology to monitor axon function. RESULTS Glycogen was present i...

The CAP Inventory (Form VI; Milner, 1986) is a 160-item, paper and pencil questionnaire that was originally designed to provide an estimate of parental risk in suspected cases of child physical abuse. The CAP Inventory is now used as a risk screening tool in a variety of assessment situations. The CAP Inventory has a third-grade reading level. Respondents are instructed to respond to each item ...

The CAP Inventory (Form VI; Milner, 1986) is a 160-item, paper and pencil questionnaire that was originally designed to provide an estimate of parental risk in suspected cases of child physical abuse. The CAP Inventory is now used as a risk screening tool in a variety of assessment situations. The CAP Inventory has a third-grade reading level. Respondents are instructed to respond to each item ...

Lippia alba is empirically used for infusions, teas, macerates, and hydroalcoholic extracts because of its antispasmodic, analgesic, sedative, and anxiolytic effects. Citral is a mixture of trans-geranial and cis-neral and is the main constituent of L. alba essential oil and possesses analgesic, anxiolytic, anticonvulsant, and sedative effects. The present study evaluated the effects of the ess...

Brown, Angus M., and Bruce R. Ransom. Neuroprotective effects of increased extracellular Ca during aglycemia in white matter. J Neurophysiol 88: 1302–1307, 2002; 10.1152/jn.00113.2002. We investigated the effects of extracellular [Ca ] ([Ca ]o) on aglycemiainduced dysfunction and injury in adult rat optic nerves. Compound action potentials (CAPs) from adult rat optic nerve were recorded in vitr...

We investigated the effects of extracellular [Ca(2+)] ([Ca(2+)](o)) on aglycemia-induced dysfunction and injury in adult rat optic nerves. Compound action potentials (CAPs) from adult rat optic nerve were recorded in vitro, and the area under the CAP was used to monitor nerve function before and after 1 h periods of aglycemia. In control artificial cerebrospinal fluid (ACSF) containing 2 mM Ca(...

Background: The cellular basis for the monophasic action potential (MAP) has long been a matter of debate. At the center of the controversy is the issue as to which of the two electrodes is the recording electrode and which is the indifferent electrode. The present study is designed to address this issue. Methods: Transmembrane action potentials (TAPs) and either intramural MAPs or contact (Fra...

PURPOSE Estrogen treatment has long been known to be of benefit in prostate cancer (CaP), but its mechanism was thought to involve merely a reduction in androgen levels. However, new evidence indicates that estrogen may exert effects on CaP cells in the absence of androgens. EXPERIMENTAL DESIGN Implantation of CaP xenografts (LuCaP 35, LuCaP 49, LuCaP 58, LuCaP 73, PC-3, and LNCaP) into intac...