Triterpenes are natural products of plants that can defend against microorganisms and various stresses. Oxidosqualene cyclase (OSC), the key rate-limiting enzyme triterpene biosynthetic pathway, catalyzes 2,3-oxidosqualene into sterols triterpenes with different skeletons through chair–boat–chair (CBC) conformation or chair–chair–chair (CCC) conformation. They were expanded in mainly by tandem ...

Abstract Human PARP2/ARTD2 is an ADP-ribosyltransferase which, when activated by 5?-phosphorylated DNA ends, catalyses poly-ADP-ribosylation of itself, other proteins and DNA. In this study, a crystal structure PARP2 in complex with activating shows that the WGR domain bridges dsDNA gap joins ends. This binding results major conformational changes, including reorganization helical fragments, re...

The article aims to review the present understanding of cognitive biases and how they play a role in mental illnesses. paper explores effect conformation bias collectivistic society psychoeducation can forwarding research backed data-driven healthcare.

Correction for ‘A study on the conformation-dependent colorimetric response of polydiacetylene supramolecules to external triggers’ by Hande E. Cingil et al. , Mater. Chem. Front. 2023, https://doi.org/10.1039/d2qm01006b.

Conformational change is believed to be important to vinculin's function at sites of cell adhesion. However, nothing is known about vinculin's conformation in living cells. Using a Forster resonance energy transfer probe that reports on changes in vinculin's conformation, we find that vinculin is in the actin-binding conformation in a peripheral band of adhesive puncta in spreading cells. Howev...

Combining SERS and statistical analysis, we demonstrated that an aptamer is a flexible molecule blocked in specific conformation to capture its analyte provided evidence for the dynamics of aptamer/protein interaction.

The average lifespan of artificial joints is 15–25 years, but it still too short for young and active patients. Human synovial albumin easily adsorbed on the surfaces joint materials has increased friction when subjected to conformational changes. Most studies have focused interaction between fluid components protein conformation not been modified, how reduce wear caused by denatured proteins. ...

The present study aimed to estimate juvenile body measurements in indigenous Uttara (U) chicken and comparisons of their estimates with Rhode Island Red (RIR), Kadaknath (K) Australorp (A) breed chickens using 400 day-old chicks. parameters were estimated for weight was recorded on an electronic balance the morning before feeding 0 20 week at 2 weeks intervals. growth rate is higher than that b...

Abstract In tumors, angiogenesis (conformation of a new vasculature from another primal one) is produced with the releasing tumor angiogenic factors hypoxic cells. These substances are distributed around micro-environment by diffusion. When they reach blood vessel bed, sprouting and branching micro-vascular network produced. capillaries will supply oxygen to cells so that their state overcome. ...

The centromere region of Saccharomyces cerevisiae chromosome III has been replaced by various DNA fragments from the centromere regions of yeast chromosomes III and XI. A 289-base pair centromere (CEN3) sequence can stabilize yeast chromosome III through mitosis and meiosis. The orientation of the centromeric fragments within chromosome III has no effect on the normal mitotic or meiotic behavio...