An estimated 276,000 babies die within four weeks of birth every year worldwide from congenital anomalies [2]. The most common severe congenital anomalies are heart defects, neural tube defects and Down Syndrome. Although congenital anomalies may be genetic, infectious, nutritional or environmental in origin, most often it is difficult to identify the exact cause [2]. In 2004, hospital costs in...

introduction congenital microgastria is an extremely rare anomaly, which is due to failure of gastric development, and causes a tubular stomach with reduced capacity. it is almost always associated with other congenital anomalies. case presentation the patient was a two-month-old boy with microgastria in association with gastroesophageal reflux, tracheomalacia, and limb defect. discussion most ...

BACKGROUND There is limited data on recurrent or persistent pneumonia in children, particularly in the developing world. This is a retrospective, cross-sectional study of children with recurrent or persistent pneumonia admitted to the Pediatric Department of Massih Daneshvari Hospital, Tehran, Iran. METHODS Children under 18 years of age, who were admitted to the hospital with pneumonia betwe...

Nowadays, quality of life is receiving an increasing attention in all scientific areas. Rett syndrome (RTT) is a rare neurological development, affecting mainly females. The congenital disease affects the central nervous system, and is one of the most common causes of severe intellectual disability. The aim of our study is to evaluate the effect of RTT on the quality of life of people who are a...

A chronic disease (e.g., diabetes, cardiovascular disease, stroke, hypertension, dementia, some cancers, rheumatological diseases, human immunodeficiency virus) can occur and cycle in flare ups throughout the lifetime. Chronic illnesses, with their effect on the patient’s symptoms, mood, and need for emotional and physical support, exert a burden on family members. Additionally, families influe...

We performed a randomized, controlled trial of intravenous immune globulin (respiratory syncytial virus [RSV] neutralizing [Nt] antibody titer of 1:950 in 5% solution) to evaluate protection against RSV-induced disease over two respiratory virus seasons. Forty-nine children (mean age at enrollment, 4.5 months) with severe congenital heart disease or bronchopulmonary dysplasia were randomized as...

OBJECTIVES There has been a growing concern over Zika virus (ZIKV) infection, particularly since a probable link between ZIKV infection during pregnancy and microcephaly in the baby was identified. The present study aimed to estimate a theoretical risk of microcephaly during pregnancy with ZIKV infection in Northeastern Brazil in 2015. METHODS Temporal distributions of microcephaly, reported ...

introduction: hearing impairment is the most frequent sensorial congenital defect in newborns and has increased to 2–4 cases per 1,000 live births. sensory-neural hearing loss (snhl) accounts for more than 90% of all hearing loss. this disorder is associated with other congenital disorders such as renal, skeletal, ocular, and cardiac disorders. given that congenital heart diseases are life-thre...