Despite the improvements in prevention of acute respiratory disease in preterm infants, the incidence of bronchopulmonary dysplasia (BPD) remains largely unchanged. Acquired lobar emphysema (ALE) is an increasingly recognized complication of advanced BPD. Barotrauma, oxygen toxicity and lung immaturity are presumed to play an important role in the development of ALE in children with BPD and mos...

Congenital lobar emphysema (CLE) is a rare developmental disorder characterized by over distension of pulmonary lobes or segments. Often CLE presents a diagnostic and therapeutic dilemma. Here, we report a case of incidentally found CLE at fetal autopsy of terminated pregnancy due to ventriculomegaly and occipital localized encephalocele detected on sonography in the second trimester. A 41year-...

PURPOSE Congenital cystic pulmonary malformations (CPM) are rare anomalies. The purpose of this study was to present our experience with CPM patients who were surgically treated in our clinic and to discuss our findings along with those from the literature. MATERIALS AND METHODS Surgical treatment was performed on 19 patients under the age of 16 who were diagnosed with CPM in our clinic betwe...

A new pathological entity is here described-a polyalveolar lobe with or without emphysemagiving rise to the clinical features of childhood lobar emphysema. A detailed and quantitative study of the airways, alveoli and arteries was carried out on the left upper lobe removed because of shortness of breath, thought to be due to 'childhood lobar emphysema'. The child was 17 days old and the radiogr...

Development of the respiratory system begins at 3 weeks gestation, and aberrations in the developmental processes may give rise to a group of structural abnormalities collectively referred to as bronchopulmonary foregut malformations (BPFMs). The common BPFMs include congenital cystic adenomatoid malformation (CCAM), pulmonary sequestration, congenital lobar emphysema, and bronchogenic cysts (B...

Congenital cystic lung lesions are a rare but clinically significant group of anomalies, including congenital cystic adenomatoid malformation (CCAM), pulmonary sequestration, congenital lobar emphysema (CLE) and bronchogenic cysts. Despite the knowledge of these lesions increasing in the last years, some aspects are still debated and controversial. The diagnosis is certainly one aspect which un...