The ampicillin group of antibiotics has among been considered to be amongst the safest for use in patient with Myasthenia gravis, although a report in 1971 suggested that such might not be the case. A recent report suggested that ampidillin may aggravate Myasthenia gravis in patients and experimental animals. We report a case of clinically controlled Myasthenia gravis, in whom the administratio...

In a case of 46-year-old woman suffering from schizophrenia for over 20 years, she experienced frequent episodes of dyspnea and confirmed as superimposed with myasthenia gravis (MG). Throughout the seven-year follow-up period, after diagnosed as MG, she has been hospitalized 6 times and also diagnosed as colorectal cancer. Authors experienced various conditions associated with untoward effects ...

A male patient with muscle weakness had clinical findings of ptosis, diplopia, proximal leg weakness, and positive repetitive nerve stimulation (RNS) test. He demonstrated positive acetylcholine receptor antibody. This lung cancer patient was presenting myasthenia gravis. The causal association between non-small-cell lung cancer and non-thymomatous myasthenia gravis has not been clarified yet. ...

Patients with generalized myasthenia gravis (MG) often have associated ventilatory muscle involvement. It is not known whether patients with isolated ocular muscle involvement have identifiable involvement of their ventilatory muscles. Most studies have assessed muscle involvement by measuring muscle strength; however, we hypothesized that measures of ventilatory muscle endurance may be more se...

negative’ myasthenia gravis. J. Neuroimmunol. 28:83–93. 8. Drachman, D.B., de Silva, S., Ramsay, D., and Pestronk, A. 1987. Humoral pathogenesis of myasthenia gravis. Ann. NY Acad. Sci. 505:90–105. 9. Drachman, D., DeSilva, S., Ramsay, D., and Pestronk, A. 1987. “Sero-negative” myasthenia gravis: a humorally mediated variant of myasthenia. Neurology. 37(Suppl. 1):214. 10. Burges, J., et al. 199...

introduction:yasthenia gravis is an autoimmune disorder resulting from a decreased number of active acetylcholine receptors at the neuromuscular junction. thymectomy is one of its current treatments. due to sensitivity of myasthenic patients to non-depolarizing muscle relaxants and also the interaction of this medication with anti-cholinestrase drugs, determining the dosage of non-depolarizing ...

The pharmacodynamics profile of a drug plays an important role in the development of a novel therapeutic agent. The above mentioned basic foundation is also applicable to the development of drugs which are directed towards the neuromuscular junction. The nicotinic acetyl choline receptor has been predominant role at the neuromuscular junction and has minor role in the central nervous system. Th...

Myasthenia gravis is occasionally associated with thymoma that needs surgical resection and may progress to severe respiratory failure. We experienced a rare case of myasthenia crisis during antiviral therapy for chronic hepatitis C, in whom mediastinal thymoma was discovered and successfully managed with surgical thymectomy and meticulous medical care.A 47-year-old-male patient complained of s...

A new form of congenital myasthenia is described. An infant whose foetal movements during pregnancy had been weak presented at birth with muscle weakness and multiple contractures of the lower limbs. The clinical course was characterised by myasthenic crises during febrile illnesses. Neurophysiological studies demonstrated a decremental response at 2-3 HZ stimulation; this effect was reversed b...

Four families each with two patients with autoimmune myasthenia gravis or related conditions are reported. All clinical forms of myasthenia gravis were represented and different disease types were found within the same family. Either one or two generations could be affected and no association with a single HLA haplotype was found. The frequency of familial autoimmune myasthenia gravis is very l...