Broadly neutralizing antibodies against rapidly evolving viruses (e.g., HIV-1 and influenza virus), often manifest antigen-binding promiscuity. Based on a recent study, we hypothesize the significance of antibody polyreactivity in neutralization viruses. We propose that contributes to toleration viral variants shortens time for generating antibodies.

MOTIVATION Sequence alignment is the problem of finding the optimal character-by-character correspondence between two sequences. It can be readily solved in O(n2) time and O(n2) space on a serial machine, or in O(n) time with O(n) space per O(n) processing elements on a parallel machine. Hirschberg's divide-and-conquer approach for finding the single best path reduces space use by a factor of n...

A new divide-and-conquer technique for disparity estimation is proposed in this paper. This technique performs feature matching following the high confidence first principle, starting with the strongest feature point in the stereo pair of scanlines. Once the first matching pair is established, the ordering constraint in disparity estimation allows the original intra-scanline matching problem to...