 Abstract—KNN classification finds k nearest neighbors of a query in training data and then predicts the class of the query as the most frequent one occurring in the neighbors. This is a typical method based on the majority rule. Although majority-rule based methods have widely and successfully been used in real applications, they can be unsuitable to the learning setting of skewed class distr...

The TATA binding protein (TBP) interacts with two transcription factor complexes, upstream activating factor (UAF) and core factor (CF), to direct transcription by RNA polymerase I (polI) in the yeast Saccharomyces cerevisiae. Previous work indicates that one function of TBP is to serve as a bridge, enabling UAF to recruit and stabilize the binding of CF (23, 24). In this work we show that, in ...

Although core, animal-reminder, and contamination disgust are viewed as distinct "types" of disgust vulnerabilities, the extent to which individual differences in the three disgust domains uniquely predict contamination-related anxiety and avoidance remains unclear. Three studies were conducted to fill this important gap in the literature. Study 1 was conducted to first determine if the three t...

This study evaluated causative factors in landslide susceptibility assessments and compared the performance of five models based on certainty factor (CF), logistic regression (LR), analytic hierarchy process (AHP), coupled CF–analytic (CF-AHP), CF–logistic (CF-LR). Kaiyang County, China, has complex geological conditions frequent disasters. Based field observations, nine influencing factors, na...

Background: Identifying lung pathogens and acute spikes in lung counts remain a challenge in the treatment of patients with cystic fibrosis (CF). Bacteria from the deep lung may be sampled from aerosols produced during coughing. Methods: A new device was used to collect and measure bacteria levels from cough aerosols of patients with CF. Sputum and oral specimens were also collected and measure...

In the United States the most common cystic fibrosis (CF) alleles known are F508, G551D, G542X, R553X, and N1303K. These mutations comprise approximately 85% of U.S. CF alleles, and their detection along with analysis of XV-2C and KM-19 restriction fragment length polymorphisms (RFLPs) can enable the determination of CF status. To facilitate studies for determining CF carrier status, we develop...

gully erosion constitutes a major problem in natural resources management and soil conservation, which causes severe land degradation in arid and semi-arid areas. therefore, determination of gully prone area and identification of gully conditioning factors can help to managers and decision makers to reduce the hazard of gully erosion. the aim of this study is to predictthe gully erosion suscept...

Identifying lung pathogens and acute spikes in lung counts Background remain a challenge in the treatment of patients with cystic fibrosis (CF). Bacteria from the deep lung may be sampled from aerosols produced during coughing. : A new device was used to collect and measure bacteria levels from Methods cough aerosols of patients with CF. Sputum and oral specimens were also collected and measure...

BACKGROUND Coelocentesis may represent the ideal technique for very early prenatal diagnosis. Although cell density in coelomic fluid (CF) is very low, the results of analyses on the cellular compartment have been proposed for prenatal diagnosis. METHODS AND RESULTS We aimed to evaluate the amount of total DNA (i.e. cellular and cell-free) in 14 samples (0.4-0.8 ml) of CF, taken from women at...

Metazoan replication-dependent histone pre-mRNAs undergo a unique 3'-cleavage reaction which does not result in mRNA polyadenylation. Although the cleavage site is defined by histone-specific factors (hairpin binding protein, a 100-kDa zinc-finger protein and the U7 snRNP), a large complex consisting of cleavage/polyadenylation specificity factor, two subunits of cleavage stimulation factor and...