ABSTRACT Physiologists often assume that mitochondria are the main producers of reactive oxygen species (ROS) in cells. Consequently, biomedicine, considered as important targets for therapeutic treatments, and evolutionary biology, they mediators life-history tradeoffs. Surprisingly, data supporting such an assumption lacking, at least partially due to technical difficulties accurately measuri...

<b><i>Objective:</i></b> Complement deposition is prevalent in kidney biopsies of patients with arterial hypertension and hypertensive nephropathy, but an association complement or involvement the pathogenesis nephropathy has not been shown to date. <b><i>Methods:</i></b> In this study, we analyzed C1q C3c a rat model overload by subtotal nephrect...