نتایج جستجو برای: controlled drug release system
تعداد نتایج: 3167043 فیلتر نتایج به سال:
Background: Tolmetin (Tol) is a pyrrole acetic acid derivative that acts as a highly effective topical anti-inflammatory agent. Topical administration of Tol is effective for the management of ocular inflammations.The aim of this study was to formulate and improve a topical ophthalmic delivery system of Tol. Materials and methods: In the present study, ocular inserts of Tol were prepared using ...
Microspheres formulated from poly (D,L-lactic-co-glycolide) (PLGA), a biodegradable polymer, have been extensively evaluated as a drug delivery system. In this study, the preparation, characterization and drug release properties of the PLGA microspheres were evaluated. Simvastatin (SIM)-loaded PLGA microspheres were prepared by oil-in-water emulsion/solvent evaporation method. The microspheres ...
Multiunit pellet systems (MUPS) are an approach to develop capsule formulation for controlled release. Capsule containing MUPS, when administered rapidly disperses in the GIT, each pellet act as a sub unit, consequently as a separate drug delivery system. Controlled release pellets which delivers the drug at a predetermined rate, at a predetermined region, reduces peak plasma fluctuations, cons...
the present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. fourier transform infrared spectroscopy (ftir) and differential scannin...
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