A cohort of 666 children who had convulsions with fever were followed to determine the risks of subsequent epilepsy. High risks were found in children with preexisting cerebral palsy or mental retardation. Other major risk factors were atypical features of the febrile convulsions (such as focal seizures) and duration of febrile seizures for 10 minuts or more. The risk of developing epilepsy by ...

Seizures or convulsions that occur during anaesthesia in veterinary patients are infrequently reported in the literature. Consequently, the incidence of such events is unknown. Several drugs commonly used in clinical veterinary anaesthesia have been shown to induce epileptiform activity in both human clinical patients and experimental candidates. The present case report describes convulsions in...

Objective: To evaluate the antiepileptic activity of aqueous extract of Centella asciatica in maximal electroshock (MES) and pentylenetetrazole (PTZ) induced convulsions. Methods: The anticonvulsant activity of leaves of Centella asciatica (200 mg/kg and 400 mg/kg) in mice was assessed using MES and PTZ induced seizure models. Abolition of tonic hind limb extension (MES and PTZ) and increase in...

1. Increases in the concentrations of lactic acid and pyruvic acid in rat brain during acute dieldrin poisoning are associated with hyperactivity of the brain, whereas an increase in the cerebral alanine concentration occurs before the convulsions. Throughout the dieldrin-induced seizure pattern, fluctuations in the concentration of brain ammonia are out of phase with the actual convulsions. 2....

PURPOSE To determine the etiology of short-term mortality in patients with status epilepticus (SE). METHODS 920 episodes of SE were recorded among 750 patients in a 10-year period. According to the clinical assessment, sequence of events that led to death in a particular case showed two major causes of death: (1) underlying disease, and (2) complications caused by convulsions, therapy or coma...

objective gastroenteritis has a diverse etiology; many pathogens can cause this condition. of the extraintestinal manifestations, one is convulsions, which may be  attributable to fever, type of bacteria, or electrolyte imbalance. to assess the risk of occurrence of convulsions, in this study we investigated the association between the paraclinical and clinical findings of children with gastroe...

introduction: epilepsy is a common central nervous system (cns) disorder characterized by seizures resulting from episodic neuronal discharges. the incidence of toxicity and refractoriness has compromised the clinical efficacy of the drugs currently used for the treatment of convulsions. thus, there is a need to search for new medicines from plant origin that are readily available and safer for...

The a-methyl and a-ethyl analogs of methionine sulfoximine, like methionine sulfoximine, induce convulsions in mice and inhibit glutamine synthetase irreversibly; cu-ethylmethionine sulfoximine is approximately 50% as inhibitory as methionine sulfoximine and a-methylmethionine sulfoximine. However, whereas cy-methylmethionine sulfoximine and methionine sulfoximine inhibit y-glutamylcysteine syn...

Epilepsy is a chronic neurological disorder which is manifested at some times and masked at others. Sleep-waking state physiology is one of the most well documented factors affecting the clinical expression or suppression of human epilepsy . Specifically, non-rapid-eye-movement (NREM) sleep and the gradual process of awakening from NREM sleep are the most vulnerable periods for seizures, especi...