The mild and effective preparation of deuterated organic molecules is an active area research due to their important applications. Herein, we report air-stable easy access copper(I) complex as catalyst for the deuteration mono-substituted alkynes. Reactions were carried out in technical solvents presence air, obtain excellent deuterium incorporation a range functionalised

Predictive catalysis was applied to the reaction of pyridinium 1,4-zwitterionic thiolates with a copper carbene. Theoretical calculations were first performed determine suitability their annulation and make predictions about performance different salts, diazo species, derivatives. With in hand, experimental conditions optimized, scope assessed, precision evaluated. Yields up 90% obtained for sy...

Formation of C–C, C–N, and C–H bonds using three heterogeneous catalysts in the form of nickel-in-charcoal (Ni/C), nickel-on-graphite (Ni/Cg), and copper-in-charcoal (Cu/C) are described.

Platinum(II) salts in combination with copper salts and molecular oxygen catalyse an unprecedented intramolecular transfer of heteroatoms to alkenes to yield aminooxygenation products under sustainable conditions.

The synthesis of acridanes and related compounds through a Cu-catalysed radical cross-dehydrogenative coupling of simple 2-[2-(arylamino)aryl]malonates is reported. This method can be further streamlined to a one-pot protocol involving the in situ fomation of the 2-[2-(arylamino)aryl]malonate by α-arylation of diethyl malonate with 2-bromodiarylamines under Pd catalysis, followed by Cu-catalyse...

The development of efficient methods for accessing fluorinated functional groups is desirable. Herein, we report a two-step method that utilizes catalytic Cu for the decarboxylative trifluoromethylation of propargyl bromodifluoroacetates. This protocol affords a mixture of propargyl trifluoromethanes and trifluoromethyl allenes.

Silver is a less expensive noble metal. Superior alkynophilicity due to π-coordination with the carbon-carbon triple bond makes silver salts ideal catalysts for alkyne-based organic reactions. This review highlights the progress in alkyne chemistry via silver catalysis primarily over the past five years (ca. 2010-2014). The discussion is developed in terms of the bond type formed with the acety...