Aims: To establish a clinical, histopathological, and genetic diagnosis in two unrelated British families with Avellino corneal dystrophy (ACD). Methods: Genomic DNA was extracted from peripheral blood leucocytes of all members participating in the study. Exons 4 and 12 of the human transforming growth factor β induced (BIGH3) gene were amplified by polymerase chain reaction. The mutation and p...

PURPOSE To compare anterior eye segment measurements and morphology obtained with two optical coherence tomography systems (TD OCT, SS OCT) in eyes with corneal dystrophies (CDs). METHODS Fifty healthy volunteers (50 eyes) and 54 patients (96 eyes) diagnosed with CD (epithelial basement membrane dystrophy, EBMD = 12 eyes; Thiel-Behnke CD = 6 eyes; lattice CD TGFBI type = 15 eyes; granular CD ...

AIM To describe unique linear deposits on the surface of posterior chamber intraocular lenses (IOLs) occurring after implantation through a hexagonal cartridge. METHODS Five ACR6D SE IOLs (Corneal Laboratories, Pringy, France) were injected/implanted through hexagonal cartridges. Two of these were injected into a petri dish and the remaining three were inserted into the evacuated capsular bag...

Three-dimensional (3-D) seismic exploration is a geophysical technique that has undergone rapid growth and development in the petroleum industry. It is a mature technology that has the potential to provide accurate volumetric images of the subsurface for interpreting the structural and stratigraphic framework of ore deposits. Under favourable circumstances, 3-D seismic methods can also provide ...

Background & Aims: This study was carried out to determine the leading indications for corneal transplantation in Kerman province. Methods: Medical records of 186 patients underwent corneal transplantation during 3 years (2004-2006) in Shafa Medical Center were evaluated retrospectively. The initial diagnosis and causes of corneal grafting were recorded. Infectious keratitis (Bacterial, Fungal,...

a r t i c l e i n f o The Early–Middle Cambrian Pioche Shale of Lincoln County, Nevada preserves a diverse array of soft-bodied ecdysozoans that are well-known from the Burgess Shale soft-bodied fauna of British Columbia, Canada. At Pioche certain genera occur both above and below the Middle Cambrian boundary, allowing a comparison of the nature of their preservation across this interval. In or...

PURPOSE To describe the morphologic features of Fuchs corneal dystrophy and compare them with those of bullous keratopathy. METHODS This was an observational case series. The study group consisted of 32 corneal buttons with a diagnosis of Fuchs dystrophy and the comparison group consisted of 22 corneal buttons with bullous keratopathy. Morphologic analysis was performed of corneal buttons fro...

Hydroxychloroquine (HCQ) is a commonly used medication for its immunosuppressive and dermatologic effects. It has known ocular side effects, which include retinopathy, corneal deposits, choroidal thinning. Herein, we report the first case of HCQ-induced hyperpigmentation sclera. A 75-year-old female presented after 10 months gradual progression painless blue-gray discoloration bilateral sclera,...