purpose: to report a case of anterior segment eye deposits in a patient on long-term chlorpromazine therapy. case report: a 34 years old man had been on chlorpromazine therapy for 5 years with a total dose of 1,100 gram. since one year ago, he presented with gradual onset of decreased visual acuity in both eyes. slit-lamp examination revealed multiple fine yellow-brown deposits on the corneal e...

Accumulating evidence supports the dogma that the corneal epithelium is regenerated by stem cells located exclusively in the limbal niche, at the corneal periphery. Accordingly, limbal stem cells (LSCs) give rise to progenitors that proliferate and migrate centripetally to repopulate the corneal epithelium, which has a short turnover. Moreover, LSC loss leads to corneal opacity and blindness, w...

Aims: Selective laser trabeculoplasty (SLT) (Lumenis, Santa Clara, CA) was developed in 1999 as a means to lower IOP in patients with glaucoma. It is a relatively safe procedure. We report a rare side effect of corneal opacity and stromal haze with corneal thinning and hyperopic shift following SLT. Presentation of Case: Case report. Results: A 50 year-old Asian male who underwent SLT OD develo...

BACKGROUND Angiogenin (ANG), a component of tears, is involved in the innate immune system and is related with inflammatory disease. We investigated whether ANG has an immune modulatory function in human corneal fibroblasts (HCFs). METHODS HCFs were cultured from excised corneal tissues. The gene or protein expression levels of interleukin (IL)-1beta (β), IL-4, IL-6, IL-8, IL-10, complements,...

the purpose of this study was to evaluate the effects of different time combinations of dexamethasoneand acetylcysteine on experimentally induced corneal ulcers in dogs. experimental corneal wounds werecreated surgically to the anterior one third of the cornea in the center of all eyes of 15 mixed breed dogs. the eyes were divided into five groups according to planned post-operative medications...

A 24-year-old male presented to our emergency department 2 h after being stung in the eye by a bee while riding a motorcycle. He had severe pain and photophobia. Slit-lamp examination showed conjunctival hyperaemia with an embedded bee stinger in deep stroma, 2 mm from of the centre of the right eye (OD) cornea. The stinger did not penetrate into the anterior chamber. Visual acuity was 3/10. Th...

PURPOSE We used a rabbit model to evaluate the interface embedded between the recipient corneas and transplanted donor corneal discs after non-Descemet's stripping automated endothelial keratoplasty (nDSAEK). METHODS Unilateral DSAEK and nDSAEK surgeries were performed on New Zealand white rabbits. In vivo confocal microscopy was performed to show: the changes in corneal endothelial cells emb...

Human cornea is the anterior transparent layer of the eye globe. It is an avascular tissue that is directly exposed to the external environment. Cornea focuses the surrounding image by refracting the light through a crystalline lens to the retina. Therefore, its clarity should be well maintained for optimal visibility [1]. Cornea is a multilayered tissue and each layer has its own specificity. ...