PURPOSE To compare wavefront-derived metrics to predict subjective quality of vision after laser in situ keratomileusis (LASIK) for myopia. SETTING Department of Ophthalmology, Goethe University, Frankfurt am Main, Germany. METHODS One month postoperatively, wavefront sensing was performed and overall subjective quality of vision assessed under 3 lighting conditions (photopic, high mesopic,...

PURPOSE To present case examples outlining the use of wavefront aberrometry for toric intraocular lens (IOL) implantation pre- and postoperatively. METHODS Twelve eyes that underwent AcrySof Toric IOL (Alcon Inc Laboratories) implantation were assessed pre- and postoperatively using the NIDEK OPD Scan II (NIDEK Co Ltd). Wavefront aberrometry, corneal topography, and objective visual quality w...

PURPOSE To study the optical changes induced by the microkeratome cut, the subsequent laser ablation, and the biomechanical healing response of the cornea in normal laser in situ keratomileusis (LASIK) eyes. DESIGN Prospective randomized clinical trial. METHODS A Hansatome microkeratome was used to cut a corneal flap in one eye (study eye) of 17 normal myopic patients and a subsequent laser...

PURPOSE To compare the clinical outcome of on-flap and off-flap epi-LASIK for moderate to high myopia. METHODS This prospective, observer-masked, randomized study included 62 eyes of 31 patients with myopia who underwent off-flap epi-LASIK (epikeratome; Moria, Antony, France) in one eye (off-flap group) and on-flap epi-LASIK in the contralateral eye (on-flap group). Corneal ablation was perfo...

PURPOSE To evaluate the variation in higher-order ocular wavefront aberrations and the Nyquist limit of resolution of the cone mosaic (N(c)) in a population of young healthy subjects and the relation to axial length (AL). SETTING Fondazione G.B. Bietti IRCCS, Rome, Italy. DESIGN Case series. METHODS An adaptive optics retinal camera prototype (rtx1) was used to image the cone mosaic. Cone...

The number of layers of a micro-holographic disk is limited by wavefront aberration which is strongly dependent on the photopolymer initiation, termination and inhibition kinetics. 3D metrology is used to validate predicted index profiles.

A method is described for analyzing point source imagery collected with various amounts of defocus to obtain wavefront slope data at the exit pupil of an imaging system. Integration of this slope data yields the system wavefront aberration function. The method is based on a geometric optics interpretation of intensity point spread function measurements in the caustic region near focus. Algorith...

PURPOSE To compare the visual and refractive outcomes after laser-assisted in situ keratomileusis (LASIK) surgery for correction of myopia or myopic astigmatism using a six-dimensional Amaris excimer laser. METHODS In this retrospective cohort study, we enrolled 47 eyes of 28 patients (age: 19-36 years) with myopia or myopic astigmatism. We used the Custom Ablation Manager protocol and perfor...

Total ocular higher order aberrations and corneal topography of myopic, emmetropic and hyperopic eyes of 675 adolescents (16.9 ± 0.7 years) were measured after cycloplegia using COAS aberrometer and Medmont videokeratoscope. Corneal higher order aberrations were computed from the corneal topography maps and lenticular (internal) higher order aberrations derived by subtraction of corneal aberrat...

PURPOSE To determine the maximum permissible torsional misalignment in wavefront-guided refractive surgery. SETTING University of Zurich, Department of Ophthalmology, Zurich, Switzerland. METHODS The effect of torsionally misaligned ablations on the optical outcome was simulated using measured wavefront aberration patterns (2nd to 6th orders) in 130 normally aberrated eyes. The calculations...