background Arginine-vasopressin(avp) is a physiological co-activator of the hypothalamus-pituitary-adrenal-axis(hpa), together with corticotrophin-releasing hormone (crh). A synthetic analogue of avp, desmopressin(ddavp) is often used as pharmacological tool to assess co-activation in health and disease. The relation between ddavp’s neuroendocrine, cardiovascular, pro-coagulatory, antidiuretic ...

UNLABELLED Mifepristone is a progesterone receptor antagonist widely used in obstetrics. The aim of the study was to focus on free corticotrophin-releasing hormone (CRH) and also describe modulation of adrenal and placental steroid hormone concentrations induced by mifepristone. METHODS Twenty-six women were enrolled in the study. They received mifepristone for termination of pregnancy. Mater...

Submit Manuscript | http://medcraveonline.com billion/year and considerable patient awareness [1,2]. GCs were first discovered as the adrenal hormone capable of fully reversing the pathology of Addison’s disease [3]. It was Philip Hench (1948) however who first noticed that female patients with rheumatoid disease showed clinical improvements when pregnant, this led to the search for some adrena...

Urocortin is a neuropeptide belonging to the corticotrophin-releasing hormone family and is expressed by eutopic and ectopic human endometrium and the last years is investigated in the field of endometriosis. The objective of this systematic review is to accumulate current evidence related to the expression of urocortin in tissue and blood samples of patients suffering from endometriosis. Liter...