This study looks at blood flow through four different right coronary arteries, which have been reconstructed from bi-plane angiograms. Five non-Newtonian blood models, as well as the usual Newtonian model of blood viscosity, are used to study the wall shear stress in each of these arteries at a particular point in the cardiac cycle. It was found that in the case of steady flow in a given artery...

Microfluidic networks represent the milestone of microfluidic devices. Recent advancements in microfluidic technologies mandate complex designs where both hydraulic resistance and pressure drop across the microfluidic network are minimized, while wall shear stress is precisely mapped throughout the network. In this work, a combination of theoretical and modeling techniques is used to construct ...

Flanged shear walls are used extensively in moderate- and high-rise buildings to resist lateral loads induced by earthquakes. The seismic performance of many buildings is, therefore, closely linked to the behavior of the reinforced concrete walls. They must be carefully designed to provide not only adequate strength, but also sufficient ductility to avoid brittle failure under strong lateral lo...

During cancer metastasis, circulating tumor cells constantly experience hemodynamic shear stress in the circulation. Cellular responses to shear stress including cell viability and proliferation thus play critical roles in cancer metastasis. Here, we developed a microfluidic approach to establish a circulatory microenvironment and studied circulating human colon cancer HCT116 cells in response ...

We analyze the main features of granular shear flow through experimental measurements in a Couette geometry and a comparison to a locally Newtonian, continuum model of granular flow. The model is based on earlier hydrodynamic models, adjusted to take into account the experimentally observed coupling between fluctuations in particle motion and mean-flow properties. Experimentally, the local velo...

Recently, Mathis et al. (2011) developed a conceptual approach that is able to predict instantaneous wall-shear stress fluctuations in turbulent boundary layers. This approach embeds the scale interaction mechanisms, namely superposition and modulation, into a wall-model capable of predicting the fluctuating component of the streamwise wall-shear stress. The present study investigates the poten...

Many wall-bounded turbulent flows are characterized by a complex interaction between the outer shear layer, the structure of which is similar to a free shear layer, and an inner layer, which is essentially a perturbed boundary layer. Examples in which such an interaction occurs are separated flows recovering from reattachment, wall jets used in the context of wall cooling, heating and separatio...

Wall-shear stress results from the relative motion of a fluid over a body surface as a consequence of the no-slip condition of the fluid in the vicinity of the wall. To determine the two-dimensional wall-shear stress distribution is of utter importance in theoretical and applied turbulence research. In this article, characteristics of the Micro-Pillar Shear-Stress Sensor MPS(3), which has been ...

Arterial wall shear stress is widely believed to influence the formation and growth of atherosclerotic plaque; however, there is currently no gold standard for its in vivo measurement. The use of phase contrast MRI has proved to be challenging due to partial-volume effects and inadequate signal-to-noise ratio at the high spatial resolutions that are required. This work evaluates the use of spir...