OBJECTIVE Evaluate, based on the evolution of new biochemical markers of cardiac damage, if electrical cardioversion (ECV) causes myocardial injury. METHODS Seventy-six patients (P) submitted to elective ECV for atrial fibrillation or atrial flutter were evaluated. Creatine phosphokinase (CPK), CK-MB activity, CK-MB mass, myoglobin and cardiac troponin I (cTnI) were measured before, and 6 and...

BACKGROUND Acute kidney injury (AKI) is a severe and preventable problem of crushed earthquake victims. Early hydration therapy started before fully removing earthquake rubbles has been claimed to play a decisive role in AKI prevention, which saves the necessity of later dialysis. However, the extent, quality, and appropriateness of its know-how are controversial. METHODS Processing clinical ...

The phorbol ester phorbol 12-myristate 13-acetate induces remarkable phenotypic changes in intestinal HT-29 M6 cells; these changes consist of loss of homotypic adhesion and inactivation of E-cadherin. In parallel, cell growth is retarded. We have transfected HT-29 M6 cells with an activated form of the conventional protein kinase Calpha (cPK-Calpha). Expression of this isoform induced the acqu...

Eight stress-susceptible and eight normal pigs weighing 35 to 50 kg were studied to determine if caffeine administration would trigger the stress syndrome and affect blood CPK levels. The pigs were littermates of Yorkshire descent. One gram of caffeine (dissolved in 10 ml of saline-sodium benzoate solution) was infused into the pigs through a jugular catheter at a rate of 1.0 ml/min. Blood samp...

Objectives Cardiac biomarkers have been studied in sepsis in the past and various mechanisms for their rise have been elucidated. However their association with severity of sepsis, mortality and myocardial dysfunction warrants further studies. We have studied three different cardiac biomarkers- troponin T (trop T), creatine phosphokinase MB isoform (CPK MB) and NT pro brain natriuretic peptide ...

Process capability indices (PCI) can be viewed as effective and excellent means of measuring product quality and performance. Several capability indices including Cp, Cpk, and Cpm are well accepted and the implementation of these techniques is successful. The indices Cpu, Cpl, and Cpk have been used previously for evaluating a multi-process product with smallerthe-better, larger-the-better, and...

BACKGROUND Purinergic receptors are cell-surface molecules that bind extracellular nucleotides, notably ATP. The P2X family includes seven nonselective ion channels with one member, P2X(7), implicated in cytolytic pore formation and cell death. MATERIALS AND METHODS We sought P2X(7) expression in mouse nephrogenesis and cpk/cpk renal cyst growth, conditions in which both proliferation and apo...

Organophosphorus (OP) poisoning is an important global health problem especially in developing countries like Egypt. . Estimation of erythrocyte cholinesterase (EChE) and butyrylcholinesterase (BChE) as an evidence of OP poisoning is costly, not regularly performed and shows wide inter-individual variability. Therefore, this study was designed to assess if serum creatine phosphokinase (CPK) can...