In this talk, we investigate extrinsic CPT violation in neutrino oscillations in matter with three flavors. Note that extrinsic CPT violation is different from intrinsic CPT violation. Extrinsic CPT violation is one way of quantifying matter effects, whereas intrinsic CPT violation would mean that the CPT invariance theorem is not valid. We present analytical formulas for the extrinsic CPT prob...

Patients treated with high doses of CPT-11 rapidly develop a cholinergic syndrome that can be alleviated by atropine. Although CPT-11 was not a substrate for acetylcholinesterase (AcChE), in vitro assays confirmed that CPT-11 inhibited both human and electric eel AcChE with apparent K(i)s of 415 and 194 nM, respectively. In contrast, human or equine butyryl-cholinesterase (BuChE) converted CPT-...

Experimental signals for indirect CPT violation in the neutral-meson systems are studied in the context of a general CPTand Lorentz-violating standard-model extension. In this explicit theory, some CPT observables depend on the meson momentum and exhibit diurnal variations. The consequences for CPT tests vary significantly with the specific experimental scenario. The wide range of possible effe...

With CPT-invariant initial conditions that commute with CPT-invariant final conditions, the respective probabilities (when defined) of a set of histories and its CPT reverse are equal, giving a CPT-symmetric universe. This leads me to question whether the asymmetry of the Gell-Mann–Hartle decoherence functional for ordinary quantum mechanics should be interpreted as an asymmetry of time . PACS ...

A theoretical study of possible signals for CPT and Lorentz violation arising in hydrogen and antihydrogen spectroscopy is described. The analysis uses a CPTand Lorentz-violating extension of quantum electrodynamics, obtained from a general Lorentz-violating extension of the minimal standard model with both CPT-even and CPT-odd terms. Certain 1S-2S transitions and hyperfine Zeeman lines exhibit...

Several water-soluble derivatives (CPT3, CPT3a-d) of camptothecin (CPT) were synthesized, among which CPT3 bearing an N,N'-dimethyl-1-aminoethylcarbamate side-chain was further conjugated with reductively eliminating structural units of indolequinone, 4-nitrobenzyl alcohol and 4-nitrofuryl alcohol to produce novel prodrugs of camptothecin (CPT4-6). All CPT derivatives were of lower cytotoxicity...

Effective teaching in pharmacology and clinical pharmacology and therapeutics (CPT) is necessary to make medical students competent prescribers. However, the current structure, delivery, and assessment of CPT education in the European Union (EU) is unknown. We sent an online questionnaire to teachers with overall responsibility for CPT education in EU medical schools. Questions focused on under...