OBJECTIVES Accumulating evidence has shown that there is a genetic contribution to obstructive sleep apnea (OSA).The objectives were to use magnetic resonance imaging (MRI) cephalometry to (1) confirm heritability of craniofacial risk factors for OSA previously shown by cephalometrics; and (2) examine the heritability of new craniofacial structures that are measurable with MRI. DESIGN A sib p...

OBJECTIVE To assess the effects of hydroxyapatite cement (HAC) on the developing feline craniofacial skeleton. DESIGN Fronto-orbital craniotomies were performed on 14 kittens and reconstructed by autograft or HAC. By design, animals in which the craniofacial skeleton was reconstructed with HAC also underwent obliteration of the left frontal sinus. After achievement of skeletal maturity, anima...

Objectives: Here, a brief overview of the state-of-the-science in dentistry, oromaxillofacial diseases especially oral cancers is given and discussion of possible implications of the stem cell hypothesis to the treatment and management part is focussed. Material and Methods: The authors used „„PUBMED‟‟ to find relevant literature written in English and published from the discovery of stem cells...

It is becoming widely accepted that volume changes in the skin and soft tissue contribute greatly to age-related facial reshaping. A significant contribution to these volume changes is the loss of craniofacial skeletal support to the overlying soft tissue. Gravity, once considered the major culprit in facial aging, is now recognized to determine the direction, rather than the extent, of tissue ...

Silicone is a synthetic polymer widely used in the biomedical industry as implantable devices since 1940, owing to its excellent mechanical properties and biocompatibility. biomaterials are renowned for their biocompatibility due inert nature hydrophobic surface. A timeline illustration shows critical development periods of using silicone varied applications. In this review, discussed along wit...

The heterotrimeric G protein subunit Gsα couples receptors to activate adenylyl cyclase and is required for the intracellular cAMP response and protein kinase A (PKA) activation. Gsα is ubiquitously expressed in many cell types; however, the role of Gsα in neural crest cells (NCCs) remains unclear. Here we report that NCCs-specific Gsα knockout mice die within hours after birth and exhibit dram...

Aim. To summarize recent studies on morphological deviations of the cervical vertebral column and associations with craniofacial morphology and head posture in nonsyndromic patients and in patients with obstructive sleep apnoea (OSA). Design. In these recent studies, visual assessment of the cervical vertebral column and cephalometric analysis of the craniofacial skeleton were performed on prof...

The study of growth and development of the facial profile is of interest to clinicians and researchers in the fields of pediatric dentistry, orthodontics, and craniofacial surgery, enabling diagnosis, planning, and evaluation of treatment. Until recently, craniofacial studies addressed facial growth, facial asymmetry, and gender differences by examining changes in size. However, size changes al...

Avian embryos, which have been studied scientifically since Aristotle, continue to persevere as invaluable research tools, especially for our understanding of the development and evolution of the craniofacial skeleton. Whether the topic is beak shape in Darwin's finches or signaling interactions that underlie bone and tooth formation, birds offer advantages for craniofacial biology that uniquel...

Abnormal orofacial functions in the period of growth and development can cause morphological anomalies of the craniofacial complex. The aim of this study was to determine the correlation between open mouth posture and morphology of craniofacial complex. The shape, size and relationships of skeletal parts of craniofacial complex were determined by analysis of lateral cephalograms in the sample o...