Precision public health is a new field driven by technological advances that enable more precise descriptions and analyses of individuals and population groups, with a view to improving the overall health of populations. This promises to lead to more precise clinical and public health practices, across the continuum of prevention, screening, diagnosis, and treatment. A phenotype is the set of o...

A Micropallet-Array-based strategy allowing the identification of cells of defined phenotype in complex mixtures, such as would be obtained from a tissue biopsy, is presented. Following the distribution of single adherent cells from the mixture on individual pedestals, termed "micropallets", immunofluorescent confocal imaging is applied to interrogate the expression of five cell surface molecules.

this study demonstrates the use of a selective and sensitive voltammetric sensor for determination of acetaminophen (ac). this was  performed by modifying a glassy carbon electrode with composite film of poly(4-vinylpyridine) and graphene sheet (p4vp/gr-gce). the redox peak currents of ac increased significantly at p4vp/gr-gce. the result was achieved by the synergistic effect of combined elect...

transforming growth factor atpha (tgf-a), parathyroid hormone-tike proteins (pthlp) and oncogene p53 proteins have all been demonstrated in a variety of human tumors anil have been implicated as causes of tumor cell aggressiveness. the present study determined the existence of these peptides and their immunohistochemicat profiles in ameloblastomas. odontogenic keratocysts and dentigerous cysts ...

distribution and allocation of resources is affected by factors such as values, norms, social stratifications, ideology, information, coercion, political challenges, and even external factors. this finding means that there is always a fundamental tendency to redirect resources toward political goals instead of public interests and development. because the resource structure is strongly influenc...

flow cytometry (fcm) was used to determine the ploidy levels of six different populationsof agropyron cristatum (l.) gaertn. (poaceae) in iran, using a diploid cultivated barley (hordeumvulgare l.) as an internal reference. according to flow cytometric data, tetraploid (2n = ± 28) andhexaploid (2n = ± 42) levels were detected among the examined populations and these results weresupported by chr...

voltammetric techniques have been considered as important methods among the analytical techniques used for the identification and determination of trace concentrations of many biological molecules such as l-ascorbic acid (aa). l-ascorbic acid is an electro-active molecule, though it is difficult to determine its value directly with a majority of electrodes made of carbon and transition metals, ...

We isolated methicillin-resistant Staphylococcus aureus (MRSA) from cows with subclinical mastitis and from a person who worked with these animals. The bovine and human strains were indistinguishable by phenotyping and genotyping methods and were of a low frequency spa type. To our knowledge, this finding indicates the first documented case of direct transmission of MRSA between cows and humans.

Genic variants are more likely to alter gene function and affect disease risk than those that occur outside genes. Variants in genes, however, might not be sufficiently covered by the existing approaches to genome-wide association studies. Our analysis of the HapMap ENCODE data indicates that this concern is valid, and that an alternative approach that focuses on genic variants provides a more ...

In this paper, we investigate a simple two-phenotype and two-patch model that incorporates both spatial dispersion and density effects in the evolutionary game dynamics. The migration rates from one patch to another are considered to be patch-dependent but independent of individual's phenotype. Our main goal is to reveal the dynamical properties of the evolutionary game in a heterogeneous patch...